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Meningococcemia in a patient coinfected with hepatitis C virus and HIV.
(Emerg Infect Dis, 2000-11)
We describe the first reported case of meningococcemia in a patient coinfected with
hepatitis C virus and HIV. Hypocomplementemia secondary to hepatic dysfunction may
have enhanced the patient's susceptibility to meningococcal ...
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity.
(Proc Natl Acad Sci U S A, 2000-02-01)
Recently, we identified a GTPase-activating protein for the ADP ribosylation factor
family of small GTP-binding proteins that we call GIT1. This protein initially was
identified as an interacting partner for the G protein-coupled ...
Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction.
(Proc Natl Acad Sci U S A, 2000-05-09)
When the heart fails, there is often a constellation of biochemical alterations of
the beta-adrenergic receptor (betaAR) signaling system, leading to the loss of cardiac
inotropic reserve. betaAR down-regulation and functional ...
Catecholamines, cardiac beta-adrenergic receptors, and heart failure.
(Circulation, 2000-04-11)
Intracoronary adenovirus-mediated delivery and overexpression of the beta(2)-adrenergic receptor in the heart : prospects for molecular ventricular assistance.
(Circulation, 2000-02-01)
BACKGROUND: Genetic modulation of ventricular function may offer a novel therapeutic
strategy for patients with congestive heart failure. Myocardial overexpression of
beta(2)-adrenergic receptors (beta(2)ARs) has been shown ...