Now showing items 1-10 of 19
HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53.
(Genes Dev, 2007-04-01)
In response to DNA damage, p53 undergoes post-translational modifications (including acetylation) that are critical for its transcriptional activity. However, the mechanism by which p53 acetylation is regulated is still ...
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
(Nature Immunology, 2007-02)
Cdc25 and Wee1: Analogous opposites?
(Cell Division, 2007-05-04)
Movement through the cell cycle is controlled by the temporally and spatially ordered activation of cyclin-dependent kinases paired with their respective cyclin binding partners. Cell cycle events occur in a stepwise fashion ...
Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells.
(J Exp Med, 2007-12-24)
Receptor editing is believed to play the major role in purging newly formed B cell compartments of autoreactivity by the induction of secondary V(D)J rearrangements. In the process of immunoglobulin heavy (H) chain editing, ...
A nucleosome-guided map of transcription factor binding sites in yeast.
(PLoS Comput Biol, 2007-11)
Finding functional DNA binding sites of transcription factors (TFs) throughout the genome is a crucial step in understanding transcriptional regulation. Unfortunately, these binding sites are typically short and degenerate, ...
The feeling of looking.
(Nat Neurosci, 2007-05)
Gene expression signatures that predict radiation exposure in mice and humans.
(PLoS Med, 2007-04)
BACKGROUND: The capacity to assess environmental inputs to biological phenotypes is limited by methods that can accurately and quantitatively measure these contributions. One such example can be seen in the context of exposure ...
Neural systems for vocal learning in birds and humans: a synopsis.
(J Ornithol, 2007-12-01)
I present here a synopsis on a hypothesis that I derived on the similarities and differences of vocal learning systems in vocal learning birds for learned song and in humans for spoken language. This hypothesis states that ...
Role of the midbrain dopaminergic system in modulation of vocal brain activation by social context.
(Eur J Neurosci, 2007-06)
In a well-studied model of social behaviour, male zebra finches sing directed song to court females and undirected song, used possibly for practice or advertisement. Although the two song types are similar, the level of ...
The pallial basal ganglia pathway modulates the behaviorally driven gene expression of the motor pathway.
(Eur J Neurosci, 2007-04)
The discrete neural network for songbird vocal communication provides an effective system to study neural mechanisms of learned motor behaviors in vertebrates. This system consists of two pathways--a vocal motor pathway ...