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Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...
Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.
(BMC Genomics, 2015-01-22)
BACKGROUND: Expression quantitative trait loci (eQTL) play an important role in the
regulation of gene expression. Gene expression levels and eQTLs are expected to vary
from tissue to tissue, and therefore multi-tissue analyses ...
Preschool anxiety disorders predict different patterns of amygdala-prefrontal connectivity at school-age.
(PLoS One, 2015)
OBJECTIVE: In this prospective, longitudinal study of young children, we examined
whether a history of preschool generalized anxiety, separation anxiety, and/or social
phobia is associated with amygdala-prefrontal dysregulation ...
Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations.
(Scientific reports, 2015-01)
Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway
may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1
and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...
Steps to Health employee weight management randomized control trial: short-term follow-up results.
(J Occup Environ Med, 2015-02)
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study,
a randomized trial to evaluate the effectiveness of two employee weight management
programs offered within Duke University and the Health ...
Nurse-led behavioral management of diabetes and hypertension in community practices: a randomized trial.
(J Gen Intern Med, 2015-05)
BACKGROUND: Several trials have demonstrated the efficacy of nurse telephone case
management for diabetes (DM) and hypertension (HTN) in academic or vertically integrated
systems. Little is known about the real-world potency ...
Preoperative predictors of extended hospital length of stay following total knee arthroplasty.
(J Arthroplasty, 2015-03)
The purpose of this study was to identify the preoperative predictors of hospital
length of stay after primary total knee arthroplasty in a patient population reflecting
current trends toward shorter hospitalization and ...
Patient expectation is the most important predictor of discharge destination after primary total joint arthroplasty.
(J Arthroplasty, 2015-04)
The purpose of this study was to identify preoperative predictors of discharge destination
after total joint arthroplasty. A retrospective study of three hundred and seventy-two
consecutive patients who underwent primary ...
Persistent high serum bicarbonate and the risk of heart failure in patients with chronic kidney disease (CKD): A report from the Chronic Renal Insufficiency Cohort (CRIC) study.
(Journal of the American Heart Association, 2015-04-20)
Serum bicarbonate varies over time in chronic kidney disease (CKD) patients, and this
variability may portend poor cardiovascular outcomes. The aim of this study was to
conduct a time-updated longitudinal analysis to evaluate ...
Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery.
(BMJ Open, 2015-05-06)
OBJECTIVES: Identification of patient subpopulations susceptible to develop myocardial
infarction (MI) or, conversely, those displaying either intrinsic cardioprotective
phenotypes or highly responsive to protective interventions ...