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Amygdala-prefrontal cortex functional connectivity during threat-induced anxiety and goal distraction.
(Biol Psychiatry, 2015-02-15)
BACKGROUND: Anxiety produced by environmental threats can impair goal-directed processing
and is associated with a range of psychiatric disorders, particularly when aversive
events occur unpredictably. The prefrontal cortex ...
Mindfulness training for smokers via web-based video instruction with phone support: a prospective observational study.
(BMC complementary and alternative medicine, 2015-03-29)
BACKGROUND:Many smokers are unable to access effective behavioral smoking cessation
therapies due to location, financial limitations, schedule, transportation issues
or other reasons. We report results from a prospective ...
Simplified Predictive Instrument to Rule Out Acute Coronary Syndromes in a High-Risk Population.
(J Am Heart Assoc, 2015-12-14)
BACKGROUND: It is unclear whether diagnostic protocols based on cardiac markers to
identify low-risk chest pain patients suitable for early release from the emergency
department can be applied to patients older than 65 years ...
Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.
(Transl Psychiatry, 2015-12-15)
Fear conditioning is an established model for investigating posttraumatic stress disorder
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event,
differing on a variety of sensory and affective ...
Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...
Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.
(BMC Genomics, 2015-01-22)
BACKGROUND: Expression quantitative trait loci (eQTL) play an important role in the
regulation of gene expression. Gene expression levels and eQTLs are expected to vary
from tissue to tissue, and therefore multi-tissue analyses ...
Cardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection?
(Ann Neurol, 2015-04)
OBJECTIVE: A study was undertaken to determine whether better cognitive functioning
at midlife among more physically fit individuals reflects neuroprotection, by which
fitness protects against age-related cognitive decline, ...
Ventricular conduction and long-term heart failure outcomes and mortality in African Americans: insights from the Jackson Heart Study.
(Circ Heart Fail, 2015-03)
BACKGROUND: QRS prolongation is associated with adverse outcomes in mostly white populations,
but its clinical significance is not well established for other groups. We investigated
the association between QRS duration and ...
Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania.
(Int J Dermatol, 2015-01)
Abnormal skin findings are identified in over 90% of human immunodeficiency virus
(HIV)-infected persons globally. A prospective cohort study of HIV-infected patients
with skin complaints commencing antiretroviral therapy ...
Preschool anxiety disorders predict different patterns of amygdala-prefrontal connectivity at school-age.
(PLoS One, 2015)
OBJECTIVE: In this prospective, longitudinal study of young children, we examined
whether a history of preschool generalized anxiety, separation anxiety, and/or social
phobia is associated with amygdala-prefrontal dysregulation ...