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Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study.
(The Lancet. Oncology, 2017-08)
BACKGROUND:Internal tandem duplication mutations in FLT3 are common in acute myeloid
leukaemia and are associated with rapid relapse and short overall survival. The clinical
benefit of FLT3 inhibitors in patients with acute ...
Clinical and pathological characteristics of HIV- and HHV-8-negative Castleman disease.
(Blood, 2017-03)
Castleman disease (CD) comprises 3 poorly understood lymphoproliferative variants
sharing several common histopathological features. Unicentric CD (UCD) is localized
to a single region of lymph nodes. Multicentric CD (MCD) ...