Now showing items 1-10 of 71
Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.
(PLoS One, 2017)
BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular disease burden. The clinical profile and outcomes of AF patients with valvular heart diseases in sub-Saharan Africa (SSA) have not ...
A conceptual framework for patient-centered fertility treatment.
(Reproductive health, 2017-09-07)
BACKGROUND:Patient-centered care is a pillar of quality health care and is important to patients experiencing infertility. In this study we used empirical, in-depth data on couples' experiences of infertility treatment decision ...
Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.
(The New England journal of medicine, 2017-06)
BACKGROUND:After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit. ...
Rationale and Design of the Lung Cancer Screening Implementation. Evaluation of Patient-Centered Care Study.
(Annals of the American Thoracic Society, 2017-10)
Screening for lung cancer using low-dose computed tomography has been demonstrated to reduce lung cancer-related mortality and is being widely implemented. Further research in this area is needed to assess the impact of ...
Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus).
(BMC biology, 2017-11-16)
The de novo assembly of repeat-rich mammalian genomes using only high-throughput short read sequencing data typically results in highly fragmented genome assemblies that limit downstream applications. Here, we present an ...
Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study.
(The Lancet. Oncology, 2017-08)
BACKGROUND:Internal tandem duplication mutations in FLT3 are common in acute myeloid leukaemia and are associated with rapid relapse and short overall survival. The clinical benefit of FLT3 inhibitors in patients with acute ...
Diffuse non-midline glioma with H3F3A K27M mutation: a prognostic and treatment dilemma.
(Acta neuropathologica communications, 2017-05-15)
Learning from 2523 trauma deaths in India- opportunities to prevent in-hospital deaths.
(BMC health services research, 2017-02-16)
A systematic analysis of trauma deaths is a step towards trauma quality improvement in Indian hospitals. This study estimates the magnitude of preventable trauma deaths in five Indian hospitals, and uses a peer-review process ...
Got spirit? The spiritual climate scale, psychometric properties, benchmarking data and future directions.
(BMC health services research, 2017-02-11)
Organizations that encourage the respectful expression of diverse spiritual views have higher productivity and performance, and support employees with greater organizational commitment and job satisfaction. Within healthcare, ...