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Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.

Anderson, DJ; Chen, LF; Fowler, Vance Garrison Jr; Moehring, Rebekah; Schmader, KE; Sexton, DJ; Sloane, Richard; ... (9 authors) (PLoS One, 2013)

BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition with estimated 30% mortality. Clinical outcomes for patients with severe infections improve when antibiotics are appropriately chosen ...

Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans.

Cernak, I; Haswell, CC; Liu, C; Marx, Christine Elizabeth; Massoglia, D; McCarthy, G; MIRECC Work Group; ... (10 authors) (Hum Brain Mapp, 2013-11)

Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic mild TBI in military veterans relies on obtaining an ...

Chikungunya as a cause of acute febrile illness in southern Sri Lanka.

Akoroda, U; Bodinayake, Champica K; Chow, A; Chua, R; Devasiri, V; Gubler, DJ; Hou, Y; ... (14 authors) (PLoS One, 2013)

BACKGROUND: Chikungunya virus (CHIKV) re-emerged in Sri Lanka in late 2006 after a 40-year hiatus. We sought to identify and characterize acute chikungunya infection (CHIK) in patients presenting with acute undifferentiated ...

Etiology of severe non-malaria febrile illness in Northern Tanzania: a prospective cohort study.

Bartlett, John A; Crump, John Andrew; Galloway, RL; Kinabo, GD; Maro, Venance P; Massung, RF; Morrissey, AB; ... (12 authors) (PLoS Negl Trop Dis, 2013)

INTRODUCTION: The syndrome of fever is a commonly presenting complaint among persons seeking healthcare in low-resource areas, yet the public health community has not approached fever in a comprehensive manner. In many areas, ...

Association between a rare novel TP53 variant (rs78378222) and melanoma, squamous cell carcinoma of head and neck and lung cancer susceptibility in non-Hispanic Whites.

Wei, Qingyi; Liu, Zhensheng; Guan, Xiaoxiang; Wang, Li-E; Sturgis, Erich M (Journal of cellular and molecular medicine, 2013-07)

Recently, several studies have investigated the association between a newly reported rare functional single nucleotide polymorphism (SNP) in TP53 (rs78378222) and cancer risk, but generated inconsistent findings. The present ...

Polymorphisms of nucleotide excision repair genes predict melanoma survival.

Wei, Qingyi; Li, Chunying; Yin, Ming; Wang, Li-E; Amos, Christopher I; Zhu, Dakai; Lee, Jeffrey E; ... (9 authors) (The Journal of investigative dermatology, 2013-07)

Melanoma is the most highly malignant skin cancer, and nucleotide excision repair (NER) is involved in melanoma susceptibility. In this analysis of 1,042 melanoma patients, we evaluated whether genetic variants of NER genes ...

Trends in anemia management in US hemodialysis patients 2004-2010.

Bandeen-Roche, K; Boulware, Ebony; Cook, Courtney; Crews, DC; DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators; Ephraim, Patti L; Jaar, BG; ... (13 authors) (BMC Nephrol, 2013-12-01)

BACKGROUND: There have been major changes in the management of anemia in US hemodialysis patients in recent years. We sought to determine the influence of clinical trial results, safety regulations, and changes in reimbursement ...