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Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction.

Akushevich, Igor; Arbeev, Konstantin; Culminskaya, IV; Kulminski, Alexander; Land, Kenneth C; Ukraintseva, Svetlana; Yashin, Anatoli I (Rejuvenation Res, 2010-02)

Multiple functions of the beta2-adrenergic receptor (ADRB2) and angiotensin-converting enzyme (ACE) genes warrant studies of their associations with aging-related phenotypes. We focus on multimarker analyses and analyses ...

Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits.

Arbeev, Konstantin; Christensen, Kaare; Elo, IT; Hadley, EC; Kulminski, Alexander; Mayeux, R; Newman, Anne B; ... (11 authors) (Mech Ageing Dev, 2011-04)

We used an approach of cumulative deficits to evaluate the rate of aging in 4954 participants of the Long-Life Family Study (LLFS) recruited in the U.S. (Boston, New York, and Pittsburgh) and Denmark. We used an array of ...