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    Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages. 

    Byers, SS; Kraus, Virginia Byers; Stabler, Thomas; Zura, Robert Douglas (Arthritis Res Ther, 2009)
    INTRODUCTION: Certain amino acids within proteins have been reported to change from the L form to the D form over time. This process is known as racemization and is most likely to occur in long-lived low-turnover tissues ...
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    Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate. 

    Barr, D; Bolognesi, Michael Paul; Catterall, JB; Kraus, Virginia Byers; Zura, Robert Douglas (Arthritis Res Ther, 2009)
    INTRODUCTION: Aging proteins undergo non-enzymatic post-translational modification, including isomerization and racemization. We hypothesized that cartilage with many long-lived components could accumulate non-enzymatically ...
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    Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance. 

    Becher, H; Chierakul, W; Day, NP; Fowler, Vance Garrison Jr; Hongsuwan, M; Limmathurotsakul, D; Mahavanakul, W; ... (16 authors) (PLoS One, 2009)
    BACKGROUND: Most information on invasive Staphylococcus aureus infections comes from temperate countries. There are considerable knowledge gaps in epidemiology, treatment, drug resistance and outcome of invasive S. aureus ...
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    The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer. 

    Wei, Qingyi; Guan, Xiaoxiang; Zhao, Hui; Niu, Jiangong; Tang, Dongfeng; Ajani, Jaffer A (BMC gastroenterology, 2009-10-16)
    Both TGF-beta1 and VEGF play a critic role in the multiple-step process of tumorgenesis of gastric cancer. Single nucleotide polymorphisms (SNPs) of the TGFB1 and VEGF genes have been associated with risk and progression ...
     

     

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    AuthorKraus, Virginia Byers (2)Zura, Robert Douglas (2)Ajani, Jaffer A (1)Barr, D (1)Becher, H (1)Bolognesi, Michael Paul (1)Byers, SS (1)Catterall, JB (1)Chierakul, W (1)Day, NP (1)... View MoreDate Issued2009 (4)TypeJournal article (4)SubjectAged (4)
    Aged, 80 and over (4)
    Humans (4)
    Middle Aged (4)
    Adult (3)Cartilage, Articular (2)Isomerism (2)Osteoarthritis, Knee (2)Adolescent (1)Age Factors (1)... View MoreAffiliation of Duke Author(s)
    Clinical Science Departments (4)
    Duke (4)
    Institutes and Centers (4)
    Medicine (4)
    School of Medicine (4)Basic Science Departments (2)Duke Molecular Physiology Institute (2)Faculty (2)Medicine, Rheumatology and Immunology (2)Orthopaedics (2)... View More