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    Trade-offs in the effects of the apolipoprotein E polymorphism on risks of diseases of the heart, cancer, and neurodegenerative disorders: insights on mechanisms from the Long Life Family Study. 

    Arbeev, Konstantin; Culminskaya, IV; Kulminski, Alexander; Province, MA; Stallard, Eric; Ukraintseva, Svetlana; Yashin, Anatoli I (Rejuvenation Res, 2015-04)
    The lack of evolutionary established mechanisms linking genes to age-related traits makes the problem of genetic susceptibility to health span inherently complex. One complicating factor is genetic trade-off. Here we focused ...
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    The role of lipid-related genes, aging-related processes, and environment in healthspan. 

    Arbeev, Konstantin; Arbeeva, L; Culminskaya, IV; Kulminski, Alexander; Stallard, Eric; Ukraintseva, Svetlana; Yashin, Anatoli I (Aging Cell, 2013-04)
    The inherent complexity of aging-related traits can temper progress in unraveling the genetic origins of healthspan. We focus on two generations in the Framingham Heart Study, the original (FHS) and offspring (FHSO) cohorts, ...
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    A new algorithm for predicting time to disease endpoints in Alzheimer's disease patients. 

    Albert, M; Blacker, D; Brandt, J; Kinosian, B; Razlighi, QR; Scarmeas, N; Stallard, Eric; ... (9 authors) (J Alzheimers Dis, 2014)
    BACKGROUND: The ability to predict the length of time to death and institutionalization has strong implications for Alzheimer's disease patients and caregivers, health policy, economics, and the design of intervention studies. ...
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    Biogenetic mechanisms predisposing to complex phenotypes in parents may function differently in their children. 

    Arbeev, Konstantin; Barmada, M; Christensen, Kaare; Kulminski, Alexander; Miljkovic, I; Stallard, Eric; Yashin, Anatoli I (J Gerontol A Biol Sci Med Sci, 2013-07)
    This study focuses on the participants of the Long Life Family Study to elucidate whether biogenetic mechanisms underlying relationships among heritable complex phenotypes in parents function in the same way for the same ...
     

     

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    Stallard, Eric (4)
    Yashin, Anatoli I (4)
    Arbeev, Konstantin (3)Kulminski, Alexander (3)Culminskaya, IV (2)Ukraintseva, Svetlana (2)Albert, M (1)Arbeeva, L (1)Barmada, M (1)Blacker, D (1)... View MoreDate Issued2013 (2)2014 (1)2015 (1)TypeJournal article (4)SubjectAged (4)Female (4)
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    Middle Aged (4)
    Aged, 80 and over (3)Adult (2)Age Factors (2)Aging (2)Genetic Predisposition to Disease (2)... View MoreAffiliation of Duke Author(s)Center for Population Health & Aging (4)
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    Duke Cancer Institute (4)Duke Population Research Center (4)Duke Population Research Institute (4)Institutes and Centers (4)Institutes and Provost's Academic Units (4)
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