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White matter compromise in veterans exposed to primary blast forces.

Haswell, CC; Hurley, RA; Hurt, SD; Lamar, CD; Morey, Rajendra A; Rowland, JA; Taber, KH (J Head Trauma Rehabil, 2015-01)

OBJECTIVE: Use diffusion tensor imaging to investigate white matter alterations associated with blast exposure with or without acute symptoms of traumatic brain injury (TBI). PARTICIPANTS: Forty-five veterans of the recent ...

A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.

Hayes, JP; Morey, Rajendra A; Tupler, LA (Neurocase, 2012-06)

Blast-related traumatic brain injury (TBI) from the Afghanistan and Iraq wars represents a significant medical concern for troops and veterans. To better understand the consequences of primary-blast injury in humans, we ...

Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.

Bancroft-Wu, V; Batrachenko, A; De Bellis, MD; Langkammer, C; Li, W; Liu, C; Morey, Rajendra A; ... (11 authors) (Hum Brain Mapp, 2014-06)

As indicated by several recent studies, magnetic susceptibility of the brain is influenced mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination and iron deposition in the brain evolve ...

Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.

Beall, SK; Brown, VM; Gold, AL; Haswell, CC; LaBar, Kevin S; McCarthy, G; Mid-Atlantic MIRECC Workgroup; ... (10 authors) (Arch Gen Psychiatry, 2012-11)

CONTEXT: Smaller hippocampal volumes are well established in posttraumatic stress disorder (PTSD), but the relatively few studies of amygdala volume in PTSD have produced equivocal results. OBJECTIVE: To assess a large cohort ...

Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.

Dunn, CE; Hamer, RM; Keefe, Francis Joseph; Kilts, Jason David; Marx, Christine Elizabeth; MIRECC Workgroup; Morey, Rajendra A; ... (13 authors) (Pain Med, 2016-01)

BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans, many of whom continue to experience persistent pain symptoms despite multiple pharmacological interventions. Preclinical data suggest ...

Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans.

Cernak, I; Haswell, CC; Liu, C; Marx, Christine Elizabeth; Massoglia, D; McCarthy, G; MIRECC Work Group; ... (10 authors) (Hum Brain Mapp, 2013-11)

Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic mild TBI in military veterans relies on obtaining an ...

Altered resting-state functional connectivity of basolateral and centromedial amygdala complexes in posttraumatic stress disorder.

Brown, VM; Gold, AL; Haswell, CC; LaBar, Kevin S; McCarthy, G; Mid-Atlantic MIRECC Workgroup; Morey, Rajendra A (Neuropsychopharmacology, 2014-01)

The amygdala is a major structure that orchestrates defensive reactions to environmental threats and is implicated in hypervigilance and symptoms of heightened arousal in posttraumatic stress disorder (PTSD). The basolateral ...