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Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...
Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania.
(Int J Dermatol, 2015-01)
Abnormal skin findings are identified in over 90% of human immunodeficiency virus
(HIV)-infected persons globally. A prospective cohort study of HIV-infected patients
with skin complaints commencing antiretroviral therapy ...
Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial.
(Trials, 2015-04-30)
BACKGROUND: Despite the high prevalence and global impact of knee osteoarthritis (KOA),
current treatments are palliative. No disease modifying anti-osteoarthritic drug (DMOAD)
has been approved. We recently demonstrated ...
Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma.
(Cancer Epidemiol Biomarkers Prev, 2015-07)
BACKGROUND: The Notch signaling pathway is constitutively activated in human cutaneous
melanoma to promote growth and aggressive metastatic potential of primary melanoma
cells. Therefore, genetic variants in Notch pathway ...
Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.
(Clin Infect Dis, 2015-11-01)
BACKGROUND: Lyme disease is diagnosed by 2-tiered serologic testing in patients with
a compatible clinical illness, but the significance of positive test results in low-prevalence
regions has not been investigated. METHODS: ...
The TALKS study to improve communication, logistical, and financial barriers to live donor kidney transplantation in African Americans: protocol of a randomized clinical trial.
(BMC Nephrol, 2015-10-09)
BACKGROUND: Live donor kidney transplantation (LDKT), an optimal therapy for many
patients with end-stage kidney disease, is underutilized, particularly by African
Americans. Potential recipient difficulties initiating and ...
Traditional medicine practices among community members with chronic kidney disease in northern Tanzania: an ethnomedical survey.
(BMC Nephrol, 2015-10-23)
BACKGROUND: In sub-Saharan Africa, chronic kidney disease (CKD) is being recognized
as a non-communicable disease (NCD) with high morbidity and mortality. In countries
like Tanzania, people access many sources, including ...
Mortality among heroin users and users of other internationally regulated drugs: A 27-year follow-up of users in the Epidemiologic Catchment Area Program household samples.
(Drug and alcohol dependence, 2015-11)
In contrast to research on more restricted samples of drug users, epidemiological
studies open up a view of death rates and survivorship of those who have tried heroin
a few times, with no acceleration toward sustained use ...
TNF rs1799964 as a Predictive Factor of Acute Toxicities in Chinese Rectal Cancer Patients Treated With Chemoradiotherapy.
(Medicine, 2015-11)
Acute toxicity is the main dose-limiting factor in the chemoradiotherapy of rectal
cancer patients and depends on several pro-inflammatory factors, including interleukin-1
(IL-1), IL-6, and tumor necrosis factor-alpha (TNF-α). ...
Cost-effectiveness analysis of the diagnosis of meniscus tears.
(Am J Sports Med, 2015-01)
BACKGROUND: Diagnostic imaging represents the fastest growing segment of costs in
the US health system. This study investigated the cost-effectiveness of alternative
diagnostic approaches to meniscus tears of the knee, a ...