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The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer.
(PloS one, 2013-01)
TNFAIP2 is a crucial gene involved in apoptosis. Single nucleotide polymorphisms (SNPs)
in its miRNA binding sites could modulate functions of the miRNA-target genes and
thus risk of cancers. In this study, we investigated ...
Thrombolysis in myocardial infarction risk score in an observation unit setting.
(Crit Pathw Cardiol, 2013-09)
OBJECTIVE: The Thrombolysis in Myocardial Infarction (TIMI) score is a validated tool
for risk stratification of acute coronary syndrome. We hypothesized that the TIMI
risk score would be able to risk stratify patients in ...
Embolization of patent foramen ovale closure devices: incidence, role of imaging in identification, potential causes, and management.
(Tex Heart Inst J, 2013)
Transcatheter patent foramen ovale (PFO) closure is an alternative to antiplatelet
or anticoagulative therapy in patients with cryptogenic stroke, and it is associated
with a small incidence of periprocedural sequelae. Because ...
Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family.
(PLoS One, 2013)
Given the importance of cardiovascular disease (CVD) to public health and the demonstrated
heritability of both disease status and its related risk factors, identifying the
genetic variation underlying these susceptibilities ...
Effect of socioeconomic status as measured by education level on survival in breast cancer clinical trials.
(Psychooncology, 2013-02)
OBJECTIVES: This paper aims to investigate the effect of socioeconomic status, as
measured by education, on the survival of breast cancer patients treated on 10 studies
conducted by the Cancer and Leukemia Group B. METHODS: ...
Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.
(J Am Heart Assoc, 2013-11-25)
BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis
in atrial fibrillation. Adoption patterns of this new agent in community practice
are unknown. METHODS AND RESULTS: We studied patterns ...
Racial differences in the prevalence and outcomes of atrial fibrillation among patients hospitalized with heart failure.
(J Am Heart Assoc, 2013-09-26)
BACKGROUND: The intersection of heart failure (HF) and atrial fibrillation (AF) is
common, but the burden of AF among black patients with HF is poorly characterized.
We sought to determine the prevalence of AF, characteristics, ...
Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.
(J Am Heart Assoc, 2013-03-19)
BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD)
patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence
of depression and anxiety. We examined whether ...
Morbidity risks among older adults with pre-existing age-related diseases.
(Exp Gerontol, 2013-12)
Multi-morbidity is common among older adults; however, for many aging-related diseases
there is no information for U.S. elderly population on how earlier-manifested disease
affects the risk of another disease manifested ...
A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke.
(J Am Heart Assoc, 2013-01-28)
BACKGROUND: We aimed to derive and validate a single risk score for predicting death
from ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage
(SAH). METHODS AND RESULTS: Data from 333 865 stroke ...