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Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck.
(PloS one, 2012-01)
Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important
role in nucleotide excision repair and participates in removal of DNA interstrand
cross-links and DNA double-strand breaks. Single nucleotide ...
Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni.
(Clin Sci (Lond), 2015-11)
Schistosomiasis is a major cause of portal hypertension worldwide. It associates with
portal fibrosis that develops during chronic infection. The mechanisms by which the
pathogen evokes these host responses remain unclear. ...
Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.
(PLoS One, 2013)
BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition
with estimated 30% mortality. Clinical outcomes for patients with severe infections
improve when antibiotics are appropriately chosen ...
Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
(J Immunol Methods, 2014-07)
A large repository of cryopreserved peripheral blood mononuclear cells (PBMCs) samples
was created to provide laboratories testing the specimens from human immunodeficiency
virus-1 (HIV-1) vaccine clinical trials the material ...
Host gene expression classifiers diagnose acute respiratory illness etiology.
(Sci Transl Med, 2016-01-20)
Acute respiratory infections caused by bacterial or viral pathogens are among the
most common reasons for seeking medical care. Despite improvements in pathogen-based
diagnostics, most patients receive inappropriate antibiotics. ...
Design of a Novel Low Cost Point of Care Tampon (POCkeT) Colposcope for Use in Resource Limited Settings.
(PLoS One, 2015)
INTRODUCTION: Current guidelines by WHO for cervical cancer screening in low- and
middle-income countries involves visual inspection with acetic acid (VIA) of the cervix,
followed by treatment during the same visit or a ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)
BACKGROUND: Disseminated tuberculosis is a major health problem in countries where
generalized human immunodeficiency virus (HIV) infection epidemics coincide with high
tuberculosis incidence rates; data are limited on patient ...
Subjective experience of sensation in anorexia nervosa.
(Behaviour research and therapy, 2013-06)
The nature of disturbance in body experience in anorexia nervosa (AN) remains poorly
operationalized despite its prognostic significance. We examined the relationship
of subjective reports of sensitivity to and behavioral ...
Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.
(Clin Infect Dis, 2015-11-01)
BACKGROUND: Lyme disease is diagnosed by 2-tiered serologic testing in patients with
a compatible clinical illness, but the significance of positive test results in low-prevalence
regions has not been investigated. METHODS: ...