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Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
(J Immunol Methods, 2014-07)
A large repository of cryopreserved peripheral blood mononuclear cells (PBMCs) samples
was created to provide laboratories testing the specimens from human immunodeficiency
virus-1 (HIV-1) vaccine clinical trials the material ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...
Design of a Novel Low Cost Point of Care Tampon (POCkeT) Colposcope for Use in Resource Limited Settings.
(PLoS One, 2015)
INTRODUCTION: Current guidelines by WHO for cervical cancer screening in low- and
middle-income countries involves visual inspection with acetic acid (VIA) of the cervix,
followed by treatment during the same visit or a ...
Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.
(Clin Infect Dis, 2015-11-01)
BACKGROUND: Lyme disease is diagnosed by 2-tiered serologic testing in patients with
a compatible clinical illness, but the significance of positive test results in low-prevalence
regions has not been investigated. METHODS: ...
A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation.
(Clin Cancer Res, 2016-01-15)
PURPOSE: Cutaneous sclerosis occurs in 20% of patients with chronic graft-versus-host
disease (GVHD) and can compromise mobility and quality of life. EXPERIMENTAL DESIGN:
We conducted a prospective, multicenter, randomized, ...
TNF rs1799964 as a Predictive Factor of Acute Toxicities in Chinese Rectal Cancer Patients Treated With Chemoradiotherapy.
(Medicine, 2015-11)
Acute toxicity is the main dose-limiting factor in the chemoradiotherapy of rectal
cancer patients and depends on several pro-inflammatory factors, including interleukin-1
(IL-1), IL-6, and tumor necrosis factor-alpha (TNF-α). ...
A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population.
(BMC cancer, 2011-01)
BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1
(APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1
promoter -141T/G variant (rs1760944) has been reported ...
Tumor necrosis factor-α induced protein 8 polymorphism and risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study.
(PloS one, 2012-01)
BACKGROUND: Non-Hodgkin's lymphoma (NHL) has been reported to be associated with autoimmune
and pro-inflammatory response, and genetic polymorphisms of candidate genes involved
in autoimmune and pro-inflammatory response ...
On the interplay of telomeres, nevi and the risk of melanoma.
(PloS one, 2012-01)
The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres
have been found to be associated with many cancers and with number of nevi, a known
risk factor for melanoma. However, shorter telomeres ...