Now showing items 1-3 of 3
Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk.
(Cancer science, 2019-06)
Pancreatic cancer (PanC) is one of the most lethal solid malignancies, and metastatic PanC is often present at the time of diagnosis. Although several high- and low-penetrance genes have been implicated in PanC, their roles ...
Life is sweet: the cell biology of glycoconjugates.
(Molecular biology of the cell, 2019-03)
Cells are dazzling in their diversity, both within and across organisms. And yet, throughout this variety runs at least one common thread: sugars. All cells on Earth, in all domains of life, are literally covered in glycans, ...
Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients.
(Translational psychiatry, 2019-07-04)
Metabolomics provides valuable tools for the study of drug effects, unraveling the mechanism of action and variation in response due to treatment. In this study we used electrochemistry-based targeted metabolomics to gain ...