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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya. 

Bloomfield, Gerald; Carter, EJ; Hogan, JW; Keter, A; Kimaiyo, S; Sang, E; Velazquez, Eric J (PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related cardiovascular risk research is largely derived ...
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Downstream coronary effects of drug-eluting stents. 

Krasuski, Richard A; Cater, George M; Devendra, Ganesh P; Wolski, Kathy; Shishehbor, Mehdi H; Nissen, Steven E; Oberti, Carlos; ... (8 authors) (Am Heart J, 2011-10)
BACKGROUND: Antiproliferative agents used in drug-eluting stents (DES) attenuate atherosclerosis, yet DES implantation has been linked to endothelial dysfunction. The downstream effects of DES on new lesion formation have ...
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The effect of gemfibrozil, niacin and cholestyramine combination therapy on metabolic syndrome in the Armed Forces Regression Study. 

Krasuski, Richard A; Devendra, Ganesh P; Cater, George; Whitney, Edwin J (Am J Med Sci, 2011-05)
INTRODUCTION: Metabolic syndrome is a powerful predictor of cardiovascular events independent of overt diabetes. Dietary restriction and weight loss modify metabolic syndrome components. This study addresses whether combination ...
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Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 

Ma, Hongxia; Wang, Li-E; Liu, Zhensheng; Sturgis, Erich M; Wei, Qingyi (BMC cancer, 2011-06-20)
Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase family plays crucial roles in carcinogenesis and progression of several cancers, including squamous cell carcinoma of the head and neck ...
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A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population. 

Zhou, Keke; Hu, Dezhi; Lu, Juan; Fan, Weiwei; Liu, Hongliang; Chen, Hongyan; Chen, Gong; ... (12 authors) (BMC cancer, 2011-01)
BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1 (APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1 promoter -141T/G variant (rs1760944) has been reported ...
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A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. 

McKay, James D; Truong, Therese; Gaborieau, Valerie; Chabrier, Amelie; Chuang, Shu-Chun; Byrnes, Graham; Zaridze, David; ... (130 authors) (PLoS genetics, 2011-03-17)
Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease. We conducted a GWAS to identify common genetic variation involved ...
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Substance use disorders and comorbid Axis I and II psychiatric disorders among young psychiatric patients: findings from a large electronic health records database. 

Wu, Li-Tzy; Gersing, Ken; Burchett, Bruce; Woody, George E; Blazer, Dan G (Journal of psychiatric research, 2011-11)
This study examined the prevalence of substance use disorders (SUDs) among psychiatric patients aged 2-17 years in an electronic health records database (N=11,457) and determined patterns of comorbid diagnoses among patients ...
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Racial/ethnic variations in substance-related disorders among adolescents in the United States. 

Wu, Li-Tzy; Woody, George E; Yang, Chongming; Pan, Jeng-Jong; Blazer, Dan G (Archives of general psychiatry, 2011-11)
While young racial/ethnic groups are the fastest growing population in the United States, data about substance-related disorders among adolescents of various racial/ethnic backgrounds are lacking.To examine the magnitude ...
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Illicit and nonmedical drug use among older adults: a review. 

Wu, Li-Tzy; Blazer, Dan G (Journal of aging and health, 2011-04)
Substance abuse among older adults is a looming public health concern. The number of Americans aged 50+ years with a substance use disorder is projected to double from 2.8 million in 2002-2006 to 5.7 million in 2020. The ...
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Depressive symptoms, substance use, and HIV-related high-risk behaviors among opioid-dependent individuals: results from the Clinical Trials Network. 

Pilowsky, Daniel J; Wu, Li-Tzy; Burchett, Bruce; Blazer, Dan G; Ling, Walter (Substance use & misuse, 2011-01)
The sample included 343 opioid-dependent adults enrolled in two national multisite studies of the National Drug Abuse Treatment Clinical Trials Network (CTN001-002). Opioid-dependent individuals were recruited from 12 sites ...
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AuthorWu, Li-Tzy (9)Blazer, Dan G (8)Rubin, David C (7)Krasuski, Richard A (5)Wei, Qingyi (5)Woody, George E (5)Arbeev, Konstantin G (4)Wang, Li-E (4)Yashin, Anatoliy I (4)Akushevich, Igor (3)... View MoreDate Issued
2011 (78)
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Humans (76)Middle Aged (41)Adult (39)Aged (25)Adolescent (24)Young Adult (24)Aged, 80 and over (10)Child (10)... View MoreAffiliation of Duke Author(s)Duke (78)School of Medicine (64)Clinical Science Departments (55)Institutes and Centers (46)Institutes and Provost's Academic Units (43)University Institutes and Centers (43)Medicine (33)Sanford School of Public Policy (29)Duke Institute for Brain Sciences (26)Trinity College of Arts & Sciences (25)... View More
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