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Increased renal dopamine and acute renal adaptation to a high-phosphate diet.
(American journal of physiology. Renal physiology, 2011-05)
The current experiments explore the role of dopamine in facilitating the acute increase
in renal phosphate excretion in response to a high-phosphate diet. Compared with a
low-phosphate (0.1%) diet for 24 h, mice ...
Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis.
(Arthritis Res Ther, 2012-04-17)
INTRODUCTION: Osteoarthritis (OA) results in pain and disability; however, preclinical
OA models often focus on joint-level changes. Gait analysis is one method used to
evaluate both preclinical OA models and OA patients. ...
Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni.
(Clin Sci (Lond), 2015-11)
Schistosomiasis is a major cause of portal hypertension worldwide. It associates with
portal fibrosis that develops during chronic infection. The mechanisms by which the
pathogen evokes these host responses remain unclear. ...
Patient-derived endothelial progenitor cells improve vascular graft patency in a rodent model.
(Acta Biomater, 2012-01)
Late outgrowth endothelial progenitor cells (EPCs) derived from the peripheral blood
of patients with significant coronary artery disease were sodded into the lumens of
small diameter expanded polytetrafluoroethylene (ePTFE) ...
A model of sequential heart and composite tissue allotransplant in rats.
(Plast Reconstr Surg, 2010-07)
BACKGROUND: Some of the 600,000 patients with solid organ allotransplants need reconstruction
with a composite tissue allotransplant, such as the hand, abdominal wall, or face.
The aim of this study was to develop a rat ...
Bioburden after Staphylococcus aureus inoculation in type 1 diabetic rats undergoing internal fixation.
(Plast Reconstr Surg, 2014-09)
SUMMARY: Fracture stabilization in the diabetic patient is associated with higher
complication rates, particularly infection and impaired wound healing, which can lead
to major tissue damage, osteomyelitis, and higher amputation ...
A Peptide Uncoupling BDNF Receptor TrkB from Phospholipase Cγ1 Prevents Epilepsy Induced by Status Epilepticus.
(Neuron, 2015-11-04)
The BDNF receptor tyrosine kinase, TrkB, underlies nervous system function in both
health and disease. Excessive activation of TrkB caused by status epilepticus promotes
development of temporal lobe epilepsy (TLE), revealing ...
Bioluminescence imaging of glucose in tissue surrounding polyurethane and glucose sensor implants.
(J Diabetes Sci Technol, 2010-09-01)
BACKGROUND: The bioluminescence technique was used to quantify the local glucose concentration
in the tissue surrounding subcutaneously implanted polyurethane material and surrounding
glucose sensors. In addition, some implants ...
Induction of anti-myelin antibodies in EAE and their possible role in demyelination.
(J Neurosci Res, 1991-12)
Experimental allergic encephalomyelitis is characterized by invasion of lymphocytes
and macrophages into the central nervous system resulting in inflammation, edema,
and demyelination. Sera from Lewis rats from 7-95 days ...
Early propranolol treatment induces lung heme-oxygenase-1, attenuates metabolic dysfunction, and improves survival following experimental sepsis.
(Crit Care, 2013-09-10)
INTRODUCTION: Pharmacological agents that block beta-adrenergic receptors have been
associated with improved outcome in burn injury. It has been hypothesized that injuries
leading to a hypermetabolic state, such as septic ...