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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.

Bloomfield, Gerald; Carter, EJ; Hogan, JW; Keter, A; Kimaiyo, S; Sang, E; Velazquez, Eric J (PLoS One, 2011)

BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related cardiovascular risk research is largely derived ...

Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records.

Bloomfield, Gerald; Hogan, JW; Holland, Thomas; Keter, A; Kimaiyo, S; Sang, E; Velazquez, Eric J (BMC Infect Dis, 2014-05-22)

BACKGROUND: Mortality among people with human immunodeficiency virus (HIV) infection is increasingly due to non-communicable causes. This has been observed mostly in developed countries and the routine care of HIV infected ...

Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.

Benoit, SR; Engel, J; Evans, Sharon E; Frederick, J; Kutty, PK; McDonald, LC; Naggie, Susanna; ... (9 authors) (Emerg Infect Dis, 2010-02)

We determined estimated incidence of and risk factors for community-associated Clostridium difficile infection (CA-CDI) among patients treated at 6 North Carolina hospitals. CA-CDI case-patients were defined as adults (>18 ...

Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.

Cho, Alex Han; Gallagher, Patrick; Ginsburg, Geoffrey Steven; Haga, Susanne B; Joy, Scott Victor; Kawamoto, Kensaku; Killeya-Jones, LA; ... (10 authors) (BMC Health Serv Res, 2012-01-18)

BACKGROUND: Type 2 diabetes is a prevalent chronic condition globally that results in extensive morbidity, decreased quality of life, and increased health services utilization. Lifestyle changes can prevent the development ...

Associations between expression levels of nucleotide excision repair proteins in lymphoblastoid cells and risk of squamous cell carcinoma of the head and neck.

Troy, Jesse; Lee, Walter; Liu, Zhensheng; Wei, Qingyi; Han, Peng; Liu, Hongliang; Shi, Qiong; ... (10 authors) (Molecular carcinogenesis, 2018-06)

Squamous cell carcinoma of head and neck (SCCHN) is one of the most common malignancies worldwide, and nucleotide excision repair (NER) is involved in SCCHN susceptibility. In this analysis of 349 newly diagnosed SCCHN patients ...

Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population.

Wei, Qingyi; Zhou, Fei; Cheng, Lei; Qiu, Li-Xin; Wang, Meng-Yun; Li, Jin; Sun, Meng-Hong; ... (11 authors) (Oncotarget, 2016-05)

The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated cancers, including gastric cancer (GCa). We evaluated associations between 10 potentially functional single nucleotide ...

A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population.

Wei, Qingyi; Wang, Meng-Yun; He, Jing; Zhu, Mei-Ling; Teng, Xiao-Yan; Li, Qiao-Xin; Sun, Meng-Hong; ... (12 authors) (Scientific reports, 2016-01-28)

AKT is an important signal transduction protein that plays a crucial role in cancer development. Therefore, we evaluated associations between single nucleotide polymorphisms (SNPs) in the AKT promoter region and gastric ...

Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study.

Bandeen-Roche, K; Boulware, Ebony; Crews, DC; DEcIDE ESRD Patient Outcomes in Renal Disease Study Investigators; Ephraim, Patti L; Jaar, BG; Liu, J; ... (16 authors) (BMC Nephrol, 2012-12-06)

BACKGROUND: Evidence is lacking to inform providers' and patients' decisions about many common treatment strategies for patients with end stage renal disease (ESRD). METHODS/DESIGN: The DEcIDE Patient Outcomes in ESRD Study ...

Trends in anemia management in US hemodialysis patients 2004-2010.

Bandeen-Roche, K; Boulware, Ebony; Cook, Courtney; Crews, DC; DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators; Ephraim, Patti L; Jaar, BG; ... (13 authors) (BMC Nephrol, 2013-12-01)

BACKGROUND: There have been major changes in the management of anemia in US hemodialysis patients in recent years. We sought to determine the influence of clinical trial results, safety regulations, and changes in reimbursement ...