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Baseline EEG pattern on continuous ICU EEG monitoring and incidence of seizures.
(J Clin Neurophysiol, 2015-04)
PURPOSE: To identify the probability of detecting nonconvulsive seizures based on
the initial pattern seen in the first 30 minutes of continuous EEG (cEEG) monitoring.
METHODS: Continuous EEG monitoring reports from 243 ...
Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.
(PLoS One, 2017)
BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular
disease burden. The clinical profile and outcomes of AF patients with valvular heart
diseases in sub-Saharan Africa (SSA) have not ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
The role of lipid-related genes, aging-related processes, and environment in healthspan.
(Aging Cell, 2013-04)
The inherent complexity of aging-related traits can temper progress in unraveling
the genetic origins of healthspan. We focus on two generations in the Framingham Heart
Study, the original (FHS) and offspring (FHSO) cohorts, ...
Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group.
(PloS one, 2018-01)
Changes in levels of cytokines and chemokines have been proposed as possible biomarkers
of tissue injury, including liver injury due to drugs. Recently, in acute drug-induced
liver injury (DILI), we showed that 19 of 27 ...
Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations.
(Hepatology (Baltimore, Md.), 2014-02)
Drug-induced liver injury (DILI) is considered to be a diagnosis of exclusion. Liver
biopsy may contribute to diagnostic accuracy, but the histological features of DILI
and their relationship to biochemical parameters and ...
Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.
(PloS one, 2019-01)
BACKGROUND:The highest burden of disease from hepatitis C virus (HCV) is found in
Southeast Asia, but our understanding of the epidemiology of infection in many heavily
burdened countries is still limited. In particular, ...
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
(Crit Care Med, 1993-01)
OBJECTIVES: To determine whether a continuous i.v. infusion of cimetidine, a histamine-2
(H2) receptor antagonist, is needed to prevent upper gastrointestinal (GI) hemorrhage
when compared with placebo and if that usage ...
Safety and efficacy of ledipasvir-sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data.
(Hepatology, 2016-02)
UNLABELLED: Black patients chronically infected with genotype 1 hepatitis C virus
(HCV) have historically had lower rates of response to interferon-based treatment
than patients of other races. In the phase 3 ION program, ...