Search
Now showing items 1-10 of 115
Predictive Modeling of Length of Hospital Stay Following Adult Spinal Deformity Correction: Analysis of 653 Patients with an Accuracy of 75% within 2 Days.
(World neurosurgery, 2018-07)
Length of stay (LOS) after surgery for adult spinal deformity (ASD) is a critical
period that allows for optimal recovery. Predictive models that estimate LOS allow
for stratification of high-risk patients.A prospectively ...
Peak Timing for Complications After Adult Spinal Deformity Surgery.
(World neurosurgery, 2018-07)
Overall complication rates for adult spinal deformity (ASD) surgery have been reported;
however, little data exist on the peak timing associated with specific complications.
This study quantifies the peak timing for multiple ...
Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck.
(PloS one, 2012-01)
Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important
role in nucleotide excision repair and participates in removal of DNA interstrand
cross-links and DNA double-strand breaks. Single nucleotide ...
Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival.
(The Journal of investigative dermatology, 2015-02)
Cutaneous melanoma (CM) is the most lethal skin cancer. The Fanconi anemia (FA) pathway
involved in DNA crosslink repair may affect CM susceptibility and prognosis. Using
data derived from published genome-wide association ...
Select Biomarkers on the Day of Anterior Cruciate Ligament Reconstruction Predict Poor Patient-Reported Outcomes at 2-Year Follow-Up: A Pilot Study.
(BioMed research international, 2018-01)
Background:The majority of patients develop posttraumatic osteoarthritis within 15
years of anterior cruciate ligament (ACL) injury. Inflammatory and chondrodegenerative
biomarkers have been associated with both pain and ...
Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells.
(Journal of orthopaedic research : official publication of the Orthopaedic Research
Society, 2011-01)
Interleukin-17 (IL-17) is a cytokine recently shown to be elevated, along with interferon-γ
(IFNγ) and tumor necrosis factor (TNFα), in degenerated and herniated intervertebral
disc (IVD) tissues, suggesting a role for these ...
The dynamics of proactive and reactive cognitive control processes in the human brain.
(J Cogn Neurosci, 2014-05)
In this study, we leveraged the high temporal resolution of EEG to examine the neural
mechanisms underlying the flexible regulation of cognitive control that unfolds over
different timescales. We measured behavioral and ...
Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans.
(Diabetes, 2010-09)
OBJECTIVE: The orexigenic gut hormone ghrelin and its receptor are present in pancreatic
islets. Although ghrelin reduces insulin secretion in rodents, its effect on insulin
secretion in humans has not been established. ...
Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands.
(PLoS One, 2009-12-30)
BACKGROUND: The MitoChip v2.0 resequencing array is an array-based technique allowing
for accurate and complete sequencing of the mitochondrial genome. No studies have
investigated mitochondrial mutation in salivary gland ...
Validation and Identification of Invasive Salmonella Serotypes in Sub-Saharan Africa by Multiplex Polymerase Chain Reaction.
(Clin Infect Dis, 2016-03-15)
Salmonella enterica serovar Typhi and nontyphoidal Salmonella (NTS) cause the majority
of bloodstream infections in sub-Saharan Africa; however, serotyping is rarely performed.
We validated a multiplex polymerase chain reaction ...