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Host gene expression classifiers diagnose acute respiratory illness etiology.
(Sci Transl Med, 2016-01-20)
Acute respiratory infections caused by bacterial or viral pathogens are among the
most common reasons for seeking medical care. Despite improvements in pathogen-based
diagnostics, most patients receive inappropriate antibiotics. ...
Estimating leptospirosis incidence using hospital-based surveillance and a population-based health care utilization survey in Tanzania.
(PLoS Negl Trop Dis, 2013)
BACKGROUND: The incidence of leptospirosis, a neglected zoonotic disease, is uncertain
in Tanzania and much of sub-Saharan Africa, resulting in scarce data on which to prioritize
resources for public health interventions ...
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)
BACKGROUND: Disseminated tuberculosis is a major health problem in countries where
generalized human immunodeficiency virus (HIV) infection epidemics coincide with high
tuberculosis incidence rates; data are limited on patient ...
Changes in HIV risk behavior and seroincidence among clients presenting for repeat HIV counseling and testing in Moshi, Tanzania.
(AIDS Care, 2012)
While HIV counseling and testing (HCT) has been considered an HIV preventive measure
in Africa, data are limited describing behavior changes following HCT. This study
evaluated behavior changes and estimated HIV seroincidence ...
Comparing actual and perceived causes of fever among community members in a low malaria transmission setting in northern Tanzania.
(Trop Med Int Health, 2013-11)
OBJECTIVE: To compare actual and perceived causes of fever in northern Tanzania. METHODS:
In a standardised survey, heads of households in 30 wards in Moshi, Tanzania, were
asked to identify the most common cause of fever ...
Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection.
(Clin Infect Dis, 2010-09-15)
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of
complicated skin and skin-structure infection (cSSSI). Increasing antimicrobial resistance
in cSSSI has led to a need for new safe and effective ...
Antibiotic overuse for acute respiratory tract infections in Sri Lanka: a qualitative study of outpatients and their physicians.
(BMC Fam Pract, 2018-03-01)
BACKGROUND: Acute respiratory tract infections (ARTIs) are a common reason for antibiotic
overuse worldwide. We previously showed that over 80% of outpatients presenting to
a tertiary care hospital in Sri Lanka ...
Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy.
(Am J Trop Med Hyg, 2015-02)
We describe the laboratory-confirmed etiologies of illness among participants in a
hospital-based febrile illness cohort study in northern Tanzania who retrospectively
met Integrated Management of Adolescent and Adult Illness ...
Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).
(Clin Infect Dis, 2010-04-15)
BACKGROUND: Invasive fungal infections (IFIs) are a major cause of morbidity and mortality
among organ transplant recipients. Multicenter prospective surveillance data to determine
disease burden and secular trends are lacking. ...
Etiology of severe non-malaria febrile illness in Northern Tanzania: a prospective cohort study.
(PLoS Negl Trop Dis, 2013)
INTRODUCTION: The syndrome of fever is a commonly presenting complaint among persons
seeking healthcare in low-resource areas, yet the public health community has not
approached fever in a comprehensive manner. In many areas, ...