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Predictive Modeling of Length of Hospital Stay Following Adult Spinal Deformity Correction: Analysis of 653 Patients with an Accuracy of 75% within 2 Days.
(World neurosurgery, 2018-07)
Length of stay (LOS) after surgery for adult spinal deformity (ASD) is a critical
period that allows for optimal recovery. Predictive models that estimate LOS allow
for stratification of high-risk patients.A prospectively ...
Peak Timing for Complications After Adult Spinal Deformity Surgery.
(World neurosurgery, 2018-07)
Overall complication rates for adult spinal deformity (ASD) surgery have been reported;
however, little data exist on the peak timing associated with specific complications.
This study quantifies the peak timing for multiple ...
Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck.
(PloS one, 2012-01)
Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important
role in nucleotide excision repair and participates in removal of DNA interstrand
cross-links and DNA double-strand breaks. Single nucleotide ...
Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival.
(The Journal of investigative dermatology, 2015-02)
Cutaneous melanoma (CM) is the most lethal skin cancer. The Fanconi anemia (FA) pathway
involved in DNA crosslink repair may affect CM susceptibility and prognosis. Using
data derived from published genome-wide association ...
Baseline EEG pattern on continuous ICU EEG monitoring and incidence of seizures.
(J Clin Neurophysiol, 2015-04)
PURPOSE: To identify the probability of detecting nonconvulsive seizures based on
the initial pattern seen in the first 30 minutes of continuous EEG (cEEG) monitoring.
METHODS: Continuous EEG monitoring reports from 243 ...
Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records.
(BMC Infect Dis, 2014-05-22)
BACKGROUND: Mortality among people with human immunodeficiency virus (HIV) infection
is increasingly due to non-communicable causes. This has been observed mostly in developed
countries and the routine care of HIV infected ...
Safety and efficacy of ledipasvir-sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data.
(Hepatology, 2016-02)
UNLABELLED: Black patients chronically infected with genotype 1 hepatitis C virus
(HCV) have historically had lower rates of response to interferon-based treatment
than patients of other races. In the phase 3 ION program, ...
Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.
(PLoS One, 2013)
BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition
with estimated 30% mortality. Clinical outcomes for patients with severe infections
improve when antibiotics are appropriately chosen ...
Host gene expression classifiers diagnose acute respiratory illness etiology.
(Sci Transl Med, 2016-01-20)
Acute respiratory infections caused by bacterial or viral pathogens are among the
most common reasons for seeking medical care. Despite improvements in pathogen-based
diagnostics, most patients receive inappropriate antibiotics. ...