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Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure. 

Tachibana, Hideo; Naga Prasad, Sathyamangla V; Lefkowitz, Robert J; Koch, Walter J; Rockman, Howard A (Circulation, 2005-02-08)
BACKGROUND: Heart failure is characterized by abnormalities in beta-adrenergic receptor (betaAR) signaling, including increased level of myocardial betaAR kinase 1 (betaARK1). Our previous studies have shown that inhibition ...

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AuthorKoch, Walter J (1)Lefkowitz, Robert J (1)Naga Prasad, Sathyamangla V (1)Rockman, Howard A (1)Tachibana, Hideo (1)Date Issued
2005 (1)
Type
Journal article (1)
Subject
Adenylyl Cyclases (1)
Animals (1)beta-Adrenergic Receptor Kinases (1)Cardiac Output, Low (1)Constriction (1)Cyclic AMP-Dependent Protein Kinases (1)
Heart (1)
Mice (1)Mice, Transgenic (1)Myocardium (1)... View MoreAffiliation of Duke Author(s)Basic Science Departments (1)Biochemistry (1)Cell Biology (1)Chemistry (1)
Clinical Science Departments (1)
Duke (1)Duke Cancer Institute (1)
Institutes and Centers (1)
Medicine (1)Medicine, Cardiology (1)... View More
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