Now showing items 1-5 of 5
Characterising phase variations in MALDI-TOF data and correcting them by peak alignment.
(Cancer Inform, 2005)
The use of MALDI-TOF mass spectrometry as a means of analyzing the proteome has been evaluated extensively in recent years. One of the limitations of this technique that has impeded the development of robust data analysis ...
Co-activation of the amygdala, hippocampus and inferior frontal gyrus during autobiographical memory retrieval.
Functional MRI was used to investigate the role of medial temporal lobe and inferior frontal lobe regions in autobiographical recall. Prior to scanning, participants generated cue words for 50 autobiographical memories and ...
When 7 transmembrane receptors are not G protein-coupled receptors.
(J Clin Invest, 2005-11)
Classically, 7 transmembrane receptors transduce extracellular signals by coupling to heterotrimeric G proteins, although recent in vitro studies have clearly demonstrated that they can also signal via G protein-independent ...
Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure.
BACKGROUND: Heart failure is characterized by abnormalities in beta-adrenergic receptor (betaAR) signaling, including increased level of myocardial betaAR kinase 1 (betaARK1). Our previous studies have shown that inhibition ...
Can prospect theory explain risk-seeking behavior by terminally ill patients?
(Med Decis Making, 2005-11)
Patients with life-threatening conditions sometimes appear to make risky treatment decisions as their condition declines, contradicting the risk-averse behavior predicted by expected utility theory. Prospect theory accommodates ...