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    An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system. 

    Ait-Azzouzene, D; Verkoczy, L; Peters, J; Gavin, A; Skog, P; Vela, JL; Nemazee, D (J Exp Med, 2005-03-07)
    Understanding immune tolerance mechanisms is a major goal of immunology research, but mechanistic studies have generally required the use of mouse models carrying untargeted or targeted antigen receptor transgenes, which ...
     

     

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    Author
    Ait-Azzouzene, D (1)
    Gavin, A (1)Nemazee, D (1)Peters, J (1)Skog, P (1)Vela, JL (1)Verkoczy, L (1)Date Issued
    2005 (1)
    Type
    Journal article (1)
    SubjectAnimals (1)Autoantigens (1)B-Lymphocytes (1)Bone Marrow Cells (1)Bone Marrow Transplantation (1)Cell Line, Tumor (1)Genes, RAG-1 (1)Immune System (1)Immune Tolerance (1)Immunoglobulin kappa-Chains (1)... View MoreAffiliation of Duke Author(s)
    Clinical Science Departments (1)
    Duke (1)Duke Human Vaccine Institute (1)
    Institutes and Centers (1)
    Medicine (1)Medicine, Duke Human Vaccine Institute (1)Pathology (1)School of Medicine (1)