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Awareness of Cervical Cancer Causes and Predeterminants of Likelihood to Screen Among Women in Haiti.
(Journal of lower genital tract disease, 2017-01)
Cervical cancer is the leading cause of cancer deaths among women in Haiti. Given
this high disease burden, we sought to better understand women's knowledge of its
causes and the sociodemographic and health correlates of ...
Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck.
(PloS one, 2012-01)
Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important
role in nucleotide excision repair and participates in removal of DNA interstrand
cross-links and DNA double-strand breaks. Single nucleotide ...
Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans.
(Diabetes, 2010-09)
OBJECTIVE: The orexigenic gut hormone ghrelin and its receptor are present in pancreatic
islets. Although ghrelin reduces insulin secretion in rodents, its effect on insulin
secretion in humans has not been established. ...
Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.
(PLoS Med, 2009-07-07)
BACKGROUND: The antibody response to HIV-1 does not appear in the plasma until approximately
2-5 weeks after transmission, and neutralizing antibodies to autologous HIV-1 generally
do not become detectable until 12 weeks ...
Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records.
(BMC Infect Dis, 2014-05-22)
BACKGROUND: Mortality among people with human immunodeficiency virus (HIV) infection
is increasingly due to non-communicable causes. This has been observed mostly in developed
countries and the routine care of HIV infected ...
Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.
(Kidney Int, 2014-12)
Focal segmental glomerulosclerosis (FSGS) is a histological lesion with many causes,
including inherited genetic defects, with significant proteinuria being the predominant
clinical finding at presentation. Mutations in ...
The TALKS study to improve communication, logistical, and financial barriers to live donor kidney transplantation in African Americans: protocol of a randomized clinical trial.
(BMC Nephrol, 2015-10-09)
BACKGROUND: Live donor kidney transplantation (LDKT), an optimal therapy for many
patients with end-stage kidney disease, is underutilized, particularly by African
Americans. Potential recipient difficulties initiating and ...
Safety and efficacy of ledipasvir-sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data.
(Hepatology, 2016-02)
UNLABELLED: Black patients chronically infected with genotype 1 hepatitis C virus
(HCV) have historically had lower rates of response to interferon-based treatment
than patients of other races. In the phase 3 ION program, ...
Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni.
(Clin Sci (Lond), 2015-11)
Schistosomiasis is a major cause of portal hypertension worldwide. It associates with
portal fibrosis that develops during chronic infection. The mechanisms by which the
pathogen evokes these host responses remain unclear. ...