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Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.

Anderson, DJ; Chen, LF; Fowler, Vance Garrison Jr; Moehring, Rebekah; Schmader, KE; Sexton, DJ; Sloane, Richard; ... (9 authors) (PLoS One, 2013)

BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition with estimated 30% mortality. Clinical outcomes for patients with severe infections improve when antibiotics are appropriately chosen ...

Host gene expression classifiers diagnose acute respiratory illness etiology.

Burke, T; Cairns, CB; Carin, Lawrence; Fowler, Vance Garrison Jr; Freeman, DH; Ginsburg, Geoffrey Steven; Glickman, Seth W; ... (24 authors) (Sci Transl Med, 2016-01-20)

Acute respiratory infections caused by bacterial or viral pathogens are among the most common reasons for seeking medical care. Despite improvements in pathogen-based diagnostics, most patients receive inappropriate antibiotics. ...

Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.

Auwaerter, PG; Boggan, Joel; Branda, JA; Chudgar, Saumil; Fowler, Vance Garrison Jr; Lantos, Paul; Nigrovic, LE; ... (9 authors) (Clin Infect Dis, 2015-11-01)

BACKGROUND: Lyme disease is diagnosed by 2-tiered serologic testing in patients with a compatible clinical illness, but the significance of positive test results in low-prevalence regions has not been investigated. METHODS: ...

Variation in the type and frequency of postoperative invasive Staphylococcus aureus infections according to type of surgical procedure.

Anderson, DJ; Arduino, JM; Choi, YI; Fowler, Vance Garrison Jr; Friedman, JY; Grussemeyer, CA; Hardy, C; ... (11 authors) (Infect Control Hosp Epidemiol, 2010-07)

OBJECTIVE: To determine the epidemiological characteristics of postoperative invasive Staphylococcus aureus infection following 4 types of major surgical procedures.design. Retrospective cohort study. SETTING: Eleven hospitals ...