Now showing items 1-10 of 35
Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53
(Proceedings of the National Academy of Sciences, 2007-11-20)
Thousands of human mobile element fragments undergo strong purifying selection near developmental genes.
(Proceedings of the National Academy of Sciences of the United States of America, 2007-05)
At least 5% of the human genome predating the mammalian radiation is thought to have evolved under purifying selection, yet protein-coding and related untranslated exons occupy at most 2% of the genome. Thus, the majority ...
A nucleosome-guided map of transcription factor binding sites in yeast.
(PLoS Comput Biol, 2007-11)
Finding functional DNA binding sites of transcription factors (TFs) throughout the genome is a crucial step in understanding transcriptional regulation. Unfortunately, these binding sites are typically short and degenerate, ...
Synchronous neural interactions assessed by magnetoencephalography: a functional biomarker for brain disorders
(Journal of Neural Engineering, 2007-12-01)
Activation of the nociceptin opioid system in rat sensory neurons produces antinociceptive effects in inflammatory pain: Involvement of inflammatory mediators
(Journal of Neuroscience Research, 2007-05-15)
Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.
(PLoS One, 2007-10-10)
BACKGROUND: Traditional imaging techniques for the localization and monitoring of bacterial infections, although reasonably sensitive, suffer from a lack of specificity. This is particularly true for musculoskeletal infections. ...
(Orphanet J Rare Dis, 2007-11-06)
Myasthenia gravis (MG) is a rare, autoimmune neuromuscular junction disorder. Contemporary prevalence rates approach 1/5,000. MG presents with painless, fluctuating, fatigable weakness involving specific muscle groups. Ocular ...
Neural systems for vocal learning in birds and humans: a synopsis.
(J Ornithol, 2007-12-01)
I present here a synopsis on a hypothesis that I derived on the similarities and differences of vocal learning systems in vocal learning birds for learned song and in humans for spoken language. This hypothesis states that ...
Microcircuits for attention.
Researchers who study the neuronal basis of cognition face a paradox. If they extract the brain, its cognitive functions cannot be assessed. On the other hand, the brain's microcircuits are difficult to study in the intact ...
The feeling of looking.
(Nat Neurosci, 2007-05)