Search
Now showing items 1-10 of 23
Provider specialty and atrial fibrillation treatment strategies in United States community practice: findings from the ORBIT-AF registry.
(J Am Heart Assoc, 2013-07-18)
BACKGROUND: The prevalence of atrial fibrillation (AF) continues to increase; however,
there are limited data describing the division of care among practitioners in the
community and whether care differs depending on provider ...
Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia.
(Mol Genet Metab, 2013-06)
Glycogen Storage Disease type Ia (GSD-Ia) in humans frequently causes delayed bone
maturation, decrease in final adult height, and decreased growth velocity. This study
evaluates the pathogenesis of growth failure and the ...
Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.
(PLoS One, 2013)
BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition
with estimated 30% mortality. Clinical outcomes for patients with severe infections
improve when antibiotics are appropriately chosen ...
Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family.
(PLoS One, 2013)
Given the importance of cardiovascular disease (CVD) to public health and the demonstrated
heritability of both disease status and its related risk factors, identifying the
genetic variation underlying these susceptibilities ...
Skeletal muscle pathology of infantile Pompe disease during long-term enzyme replacement therapy.
(Orphanet J Rare Dis, 2013-06-20)
BACKGROUND: Pompe disease is an autosomal recessive metabolic neuromuscular disorder
caused by a deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). It has
long been believed that the underlying pathology leading ...
Hazard-rate analysis and patterns of recurrence in early stage melanoma: moving towards a rationally designed surveillance strategy.
(PLoS One, 2013)
BACKGROUND: While curable at early stages, few treatment options exist for advanced
melanoma. Currently, no consensus exists regarding the optimal surveillance strategy
for patients after resection. The objectives of this ...
Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.
(J Am Heart Assoc, 2013-11-25)
BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis
in atrial fibrillation. Adoption patterns of this new agent in community practice
are unknown. METHODS AND RESULTS: We studied patterns ...
Variability in performance measures for assessment of hypertension control.
(Am Heart J, 2013-05)
BACKGROUND: Definitions of multiple performance measures exist for the assessment
of blood pressure control; however, limited data on how these technical variations
may affect actual measured performance are available. METHODS: ...
Racial differences in the prevalence and outcomes of atrial fibrillation among patients hospitalized with heart failure.
(J Am Heart Assoc, 2013-09-26)
BACKGROUND: The intersection of heart failure (HF) and atrial fibrillation (AF) is
common, but the burden of AF among black patients with HF is poorly characterized.
We sought to determine the prevalence of AF, characteristics, ...
Who enrolls in the Medicare Part D prescription drug benefit program? Medication use among patients with heart failure.
(J Am Heart Assoc, 2013-09-11)
BACKGROUND: Dispensing data from Medicare Part D standalone prescription drug plans
are now available, but characteristics of enrollees with heart failure have not been
well described. METHODS AND RESULTS: We identified ...