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Now showing items 91-100 of 103
Comparing Inverse Probability of Treatment Weighting and Instrumental Variable Methods for the Evaluation of Adenosine Diphosphate Receptor Inhibitors After Percutaneous Coronary Intervention.
(JAMA cardiology, 2016-09)
IMPORTANCE:There is increasing interest in performing comparative effectiveness analyses
in large observational databases, yet these analyses must adjust for treatment selection
issues. OBJECTIVES:To conduct comparative ...
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.
(Circ Cardiovasc Genet, 2010-04)
BACKGROUND: Molecular tools may provide insight into cardiovascular risk. We assessed
whether metabolites discriminate coronary artery disease (CAD) and predict risk of
cardiovascular events. METHODS AND RESULTS: We performed ...
Risks and Benefits Associated With Prestroke Antiplatelet Therapy Among Patients With Acute Ischemic Stroke Treated With Intravenous Tissue Plasminogen Activator.
(JAMA neurology, 2016-01)
Intravenous tissue plasminogen activator (tPA) is known to improve outcomes in ischemic
stroke; however, many patients may have been receiving antiplatelet therapy before
acute ischemic stroke and could face an increased ...
Racial/Ethnic and Sex Differences in Emergency Medical Services Transport Among Hospitalized US Stroke Patients: Analysis of the National Get With The Guidelines-Stroke Registry.
(Journal of the American Heart Association, 2015-08-12)
Differences in activation of emergency medical services (EMS) may contribute to racial/ethnic
and sex disparities in stroke outcomes. The purpose of this study was to determine
whether EMS use varied by race/ethnicity and ...
Evolutionary Divergence of Gene and Protein Expression in the Brains of Humans and Chimpanzees.
(Genome Biol Evol, 2015-07-10)
Although transcriptomic profiling has become the standard approach for exploring molecular
differences in the primate brain, very little is known about how the expression levels
of gene transcripts relate to downstream protein ...
Absence of July Phenomenon in Acute Ischemic Stroke Care Quality and Outcomes.
(Journal of the American Heart Association, 2018-01-31)
BACKGROUND:Lower care quality and an increase in adverse outcomes as a result of new
medical trainees is a concept well rooted in popular belief, termed the "July phenomenon."
Whether this phenomenon occurs in acute ischemic ...
Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.
(J Am Heart Assoc, 2013-03-19)
BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD)
patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence
of depression and anxiety. We examined whether ...
Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.
(Psychosom Med, 2010-04)
OBJECTIVES: To assess the effects of aerobic exercise training on neurocognitive performance.
Although the effects of exercise on neurocognition have been the subject of several
previous reviews and meta-analyses, they have ...
Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure.
(Hypertension, 2010-06)
High blood pressure increases the risks of stroke, dementia, and neurocognitive dysfunction.
Although aerobic exercise and dietary modifications have been shown to reduce blood
pressure, no randomized trials have examined ...
Cardiovascular and Limb Outcomes in Patients With Diabetes and Peripheral Artery Disease: The EUCLID Trial.
(Journal of the American College of Cardiology, 2018-12)
BACKGROUND:Diabetes confers an increased risk for atherosclerotic cardiovascular disease,
but less is known about the independent risk diabetes confers on major cardiovascular
and limb events in patients with symptomatic ...