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Now showing items 11-20 of 23
Dominance, politics, and physiology: voters' testosterone changes on the night of the 2008 United States presidential election.
(PLoS One, 2009-10-21)
BACKGROUND: Political elections are dominance competitions. When men win a dominance
competition, their testosterone levels rise or remain stable to resist a circadian
decline; and when they lose, their testosterone levels ...
beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.
(J Clin Invest, 2009-05)
Nicotinic acid is one of the most effective agents for both lowering triglycerides
and raising HDL. However, the side effect of cutaneous flushing severely limits patient
compliance. As nicotinic acid stimulates the GPCR ...
Histone modifications within the human X centromere region.
(PLoS One, 2009-08-12)
Human centromeres are multi-megabase regions of highly ordered arrays of alpha satellite
DNA that are separated from chromosome arms by unordered alpha satellite monomers
and other repetitive elements. Complexities in assembling ...
Using decision analysis to improve malaria control policy making.
(Health Policy, 2009-10)
Malaria and other vector-borne diseases represent a significant and growing burden
in many tropical countries. Successfully addressing these threats will require policies
that expand access to and use of existing control ...
The toxicology of climate change: environmental contaminants in a warming world.
(Environ Int, 2009-08)
Climate change induced by anthropogenic warming of the earth's atmosphere is a daunting
problem. This review examines one of the consequences of climate change that has only
recently attracted attention: namely, the effects ...
Resolving response, decision, and strategic control: evidence for a functional topography in dorsomedial prefrontal cortex.
(J Neurosci, 2009-10-21)
The dorsomedial prefrontal cortex (DMPFC) plays a central role in aspects of cognitive
control and decision making. Here, we provide evidence for an anterior-to-posterior
topography within the DMPFC using tasks that evoke ...
Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer.
(Journal of experimental & clinical cancer research : CR, 2009-06-30)
Some TGFB1 and VEGF polymorphisms are believed to be functional. Given that these
genes are involved in tumor growth and progression including angiogenesis, dissemination,
and invasiveness, we hypothesized that ...
The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer.
(BMC gastroenterology, 2009-10-16)
Both TGF-beta1 and VEGF play a critic role in the multiple-step process of tumorgenesis
of gastric cancer. Single nucleotide polymorphisms (SNPs) of the TGFB1 and VEGF genes
have been associated with risk and progression ...
Common genetic variation and the control of HIV-1 in humans.
(PLoS Genet, 2009-12)
To extend the understanding of host genetic determinants of HIV-1 control, we performed
a genome-wide association study in a cohort of 2,554 infected Caucasian subjects.
The study was powered to detect common genetic variants ...