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Now showing items 11-20 of 32
Trends in anemia management in US hemodialysis patients 2004-2010.
(BMC Nephrol, 2013-12-01)
BACKGROUND: There have been major changes in the management of anemia in US hemodialysis
patients in recent years. We sought to determine the influence of clinical trial results,
safety regulations, and changes in reimbursement ...
Smoking and opioid detoxification: behavioral changes and response to treatment.
(Nicotine & tobacco research : official journal of the Society for Research on Nicotine
and Tobacco, 2013-10)
The relevance of tobacco use in opioid addiction (OA) has generated a demand for available
and more effective interventions. Thus, further analysis of less explored nicotine-opioid
clinical interactions is warranted.A post-hoc ...
Variability in performance measures for assessment of hypertension control.
(Am Heart J, 2013-05)
BACKGROUND: Definitions of multiple performance measures exist for the assessment
of blood pressure control; however, limited data on how these technical variations
may affect actual measured performance are available. METHODS: ...
Alglucosidase alfa enzyme replacement therapy as a therapeutic approach for glycogen storage disease type III.
(Mol Genet Metab, 2013-02)
We investigated the feasibility of using recombinant human acid-α glucosidase (rhGAA,
Alglucosidase alfa), an FDA approved therapy for Pompe disease, as a treatment approach
for glycogen storage disease type III (GSD III). ...
Using electronic health records data to assess comorbidities of substance use and psychiatric diagnoses and treatment settings among adults.
(Journal of psychiatric research, 2013-04)
To examine prevalences of substance use disorders (SUD) and comprehensive patterns
of comorbidities among psychiatric patients ages 18-64 years (N = 40,099) in an electronic
health records (EHR) database.DSM-IV diagnoses ...
Tobacco use among Asian Americans, Native Hawaiians/Pacific Islanders, and mixed-race individuals: 2002-2010.
(Drug and alcohol dependence, 2013-09)
Non-Hispanic Asian Americans, Native Hawaiians/Pacific Islanders (NHs/PIs), and mixed-race
individuals are the fastest growing segments of the US population. We examined prevalences
and correlates of tobacco use among these ...
Hazard-rate analysis and patterns of recurrence in early stage melanoma: moving towards a rationally designed surveillance strategy.
(PLoS One, 2013)
BACKGROUND: While curable at early stages, few treatment options exist for advanced
melanoma. Currently, no consensus exists regarding the optimal surveillance strategy
for patients after resection. The objectives of this ...
Fibroblast growth factor 23 is not associated with and does not induce arterial calcification.
(Kidney international, 2013-06)
Elevated fibroblast growth factor 23 (FGF23) is associated with cardiovascular disease
in patients with chronic kidney disease. As a potential mediating mechanism, FGF23
induces left ventricular hypertrophy; however, its ...
Skeletal muscle pathology of infantile Pompe disease during long-term enzyme replacement therapy.
(Orphanet J Rare Dis, 2013-06-20)
BACKGROUND: Pompe disease is an autosomal recessive metabolic neuromuscular disorder
caused by a deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). It has
long been believed that the underlying pathology leading ...
Algorithm for the early diagnosis and treatment of patients with cross reactive immunologic material-negative classic infantile pompe disease: a step towards improving the efficacy of ERT.
(PLoS One, 2013)
OBJECTIVE: Although enzyme replacement therapy (ERT) is a highly effective therapy,
CRIM-negative (CN) infantile Pompe disease (IPD) patients typically mount a strong
immune response which abrogates the efficacy of ERT, ...