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Now showing items 11-20 of 30
Construct and differential item functioning in the assessment of prescription opioid use disorders among American adolescents.
(Journal of the American Academy of Child and Adolescent Psychiatry, 2009-05)
OBJECTIVE:To examine the psychometric properties of diagnostic criteria for prescription
analgesic opioid use disorders (OUDs) and to identify background predictors of a latent
continuum for OUD liability. METHOD:Data were ...
Nonprescription use of pain relievers by middle-aged and elderly community-living adults: National Survey on Drug Use and Health.
(Journal of the American Geriatrics Society, 2009-07)
To estimate the frequency, distribution, and correlates of nonprescription use of
pain relievers by middle-aged and elderly persons in the United States.Cross-sectional
data analysis of a national community survey.The 2005 ...
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.
(PLoS Med, 2009-07-07)
BACKGROUND: The antibody response to HIV-1 does not appear in the plasma until approximately
2-5 weeks after transmission, and neutralizing antibodies to autologous HIV-1 generally
do not become detectable until 12 weeks ...
Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer.
(Journal of experimental & clinical cancer research : CR, 2009-06-30)
Some TGFB1 and VEGF polymorphisms are believed to be functional. Given that these
genes are involved in tumor growth and progression including angiogenesis, dissemination,
and invasiveness, we hypothesized that ...
The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer.
(BMC gastroenterology, 2009-10-16)
Both TGF-beta1 and VEGF play a critic role in the multiple-step process of tumorgenesis
of gastric cancer. Single nucleotide polymorphisms (SNPs) of the TGFB1 and VEGF genes
have been associated with risk and progression ...
Serial dilution curve: a new method for analysis of reverse phase protein array data.
(Bioinformatics (Oxford, England), 2009-03)
Reverse phase protein arrays (RPPAs) are a powerful high-throughput tool for measuring
protein concentrations in a large number of samples. In RPPA technology, the original
samples are often diluted successively multiple ...
Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study.
(Br J Cancer, 2009-12-15)
BACKGROUND: We evaluated bevacizumab with metronomic etoposide among recurrent malignant
glioma patients in a phase 2, open-label trial. METHODS: A total of 59 patients, including
27 with glioblastoma (GBM) and 32 with grade ...
Early outcomes following low dose naltrexone enhancement of opioid detoxification.
(The American journal on addictions, 2009-03)
Although withdrawal severity and treatment completion are the initial focus of opioid
detoxification, post-detoxification outcome better defines effective interventions.
Very low dose naltrexone (VLNTX) in addition to methadone ...
MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy.
(Cancer Res, 2009-10-01)
Loss of PTEN and activation of phosphoinositide 3-kinase are commonly observed in
advanced prostate cancer. Inhibition of mammalian target of rapamycin (mTOR), a downstream
target of phosphoinositide 3-kinase signaling, ...