Now showing items 11-14 of 14
Sequence variations in DNA repair gene XPC is associated with lung cancer risk in a Chinese population: a case-control study.
(BMC cancer, 2007-01)
BACKGROUND: The nucleotide excision repair (NER) protein, xeroderma pigmentosum C (XPC), participates in recognizing DNA lesions and initiating DNA repair in response to DNA damage. Because mutations in XPC cause a high ...
Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer.
(Journal of experimental & clinical cancer research : CR, 2009-06-30)
Some TGFB1 and VEGF polymorphisms are believed to be functional. Given that these genes are involved in tumor growth and progression including angiogenesis, dissemination, and invasiveness, we hypothesized that ...
The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer.
(BMC gastroenterology, 2009-10-16)
Both TGF-beta1 and VEGF play a critic role in the multiple-step process of tumorgenesis of gastric cancer. Single nucleotide polymorphisms (SNPs) of the TGFB1 and VEGF genes have been associated with risk and progression ...
Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration.
(PLoS One, 2008-05-07)
The objective of this study was to determine if MTND2*LHON4917G (4917G), a specific non-synonymous polymorphism in the mitochondrial genome previously associated with neurodegenerative phenotypes, is associated with increased ...