Now showing items 11-20 of 8060
Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.
(Cell host & microbe, 2018-06)
HIV-1 broadly neutralizing antibodies (bnAbs) require high levels of activation-induced cytidine deaminase (AID)-catalyzed somatic mutations for optimal neutralization potency. Probable mutations occur at sites of frequent ...
Physical Activity, Sedentary Behavior, and Retirement: The Multi-Ethnic Study of Atherosclerosis.
(American journal of preventive medicine, 2018-06)
Physical activity and sedentary behavior are major risk factors for chronic disease. These behaviors may change at retirement, with implications for health in later life. The study objective was to describe longitudinal ...
A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications.
(British journal of anaesthesia, 2018-05)
There is a need for robust, clearly defined, patient-relevant outcome measures for use in randomised trials in perioperative medicine. Our objective was to establish standard outcome measures for postoperative pulmonary ...
Perioperative fluid and hemodynamic management within an enhanced recovery pathway.
(Journal of surgical oncology, 2017-10)
Goal-directed fluid therapy (GDFT) seeks to improve outcomes through individualized optimization of oxygen delivery using IV fluid and vasoactive infusions. Trials of GDFT show clinical benefits over traditional liberal ...
The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis
(Developmental Biology, 2017-04)
Enhanced Recovery and the Changing Landscape of Major Abdominal Surgery
(Anesthesiology Clinics, 2015-01-01)
American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Gastrointestinal Dysfunction Within an Enhanced Recovery Pathway for Elective Colorectal Surgery.
(Anesthesia and analgesia, 2018-06)
The primary driver of length of stay after bowel surgery, particularly colorectal surgery, is the time to return of gastrointestinal (GI) function. Traditionally, delayed GI recovery was thought to be a routine and unavoidable ...
Gestural Economies and Production Pedagogies in Deaf West’s Spring Awakening
(TDR/The Drama Review, 2016-06)
In Deaf West’s Broadway revival of Spring Awakening, embodied gestures expose and challenge representational and infrastructural norms that drive commercial musical theatre. The company’s blend of ASL and spoken text extends ...
Strong Selection at MHC in Mexicans since Admixture.
(PLoS genetics, 2016-02-10)
Mexicans are a recent admixture of Amerindians, Europeans, and Africans. We performed local ancestry analysis of Mexican samples from two genome-wide association studies obtained from dbGaP, and discovered that at the MHC ...
Systematic review and consensus definitions for standardised endpoints in perioperative medicine: postoperative cancer outcomes.
(British journal of anaesthesia, 2018-07)
The Standardising Endpoints for Perioperative Medicine group was established to derive an appropriate set of endpoints for use in clinical trials related to anaesthesia and perioperative medicine. Anaesthetic or analgesic ...