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    Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration. 

    Iannaccone, Alessandro; Hollingsworth, TJ; Koirala, Diwa; New, David D; Lenchik, Nataliya I; Beranova-Giorgianni, Sarka; Gerling, Ivan C; ... (9 authors) (Experimental eye research, 2017-02)
    We report on a novel autoantigen expressed in human macular tissues, identified following an initial Western blot (WB)-based screening of sera from subjects with age-related macular degeneration (AMD) for circulating ...
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    Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations. 

    Wei, Qingyi; Zhu, Jinhong; Wang, Mengyun; Zhu, Meiling; He, Jin; Wang, Jiu-Cun; Jin, Li; ... (9 authors) (Scientific reports, 2015-01)
    Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1 and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...
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    Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck. 

    Liu, Zhensheng; Wei, Qingyi; Yu, Hongping; Huang, Yu-Jing; Yin, Ming; Wang, Li-E (PloS one, 2012-01)
    Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important role in nucleotide excision repair and participates in removal of DNA interstrand cross-links and DNA double-strand breaks. Single nucleotide ...
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    Semi-quantitative MRI biomarkers of knee osteoarthritis progression in the FNIH biomarkers consortium cohort - Methodologic aspects and definition of change. 

    Kraus, Virginia; Roemer, Frank W; Guermazi, Ali; Collins, Jamie E; Losina, Elena; Nevitt, Michael C; Lynch, John A; ... (10 authors) (BMC musculoskeletal disorders, 2016-11-10)
    To describe the scoring methodology and MRI assessments used to evaluate the cross-sectional features observed in cases and controls, to define change over time for different MRI features, and to report the extent of changes ...
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    Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy. 

    Liu, Zhensheng; Wei, Qingyi; Yin, Ming; Liao, Zhongxing; Huang, Yu-Jing; Yuan, Xianglin; Gomez, Daniel; ... (8 authors) (PloS one, 2011-01)
    The repair of DNA double-strand breaks (DSBs) is the major mechanism to maintain genomic stability in response to irradiation. We hypothesized that genetic polymorphisms in DSB repair genes may affect clinical outcomes among ...
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    The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer. 

    Liu, Zhensheng; Wei, Qingyi; Xu, Yu; Ma, Hongxia; Yu, Hongping; Wang, Li-E; Tan, Dongfeng; ... (11 authors) (PloS one, 2013-01)
    TNFAIP2 is a crucial gene involved in apoptosis. Single nucleotide polymorphisms (SNPs) in its miRNA binding sites could modulate functions of the miRNA-target genes and thus risk of cancers. In this study, we investigated ...
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    Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 

    Liu, Zhensheng; Wei, Qingyi; Ma, Hongxia; Wang, Li-E; Sturgis, Erich M (BMC cancer, 2011-06-20)
    Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase family plays crucial roles in carcinogenesis and progression of several cancers, including squamous cell carcinoma of the head and neck ...
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    Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer. 

    Liu, Zhensheng; Wei, Qingyi; Han, Chan H; Huang, Yu-Jing; Lu, Karen H; Mills, Gordon B; Wang, Li-E (Journal of experimental & clinical cancer research : CR, 2011-01-07)
    SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ...
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    Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival. 

    Liu, Zhensheng; Wei, Qingyi; Yin, Jieyun; Liu, Hongliang; Wang, Li-E; Chen, Wei V; Zhu, Dakai; ... (10 authors) (The Journal of investigative dermatology, 2015-02)
    Cutaneous melanoma (CM) is the most lethal skin cancer. The Fanconi anemia (FA) pathway involved in DNA crosslink repair may affect CM susceptibility and prognosis. Using data derived from published genome-wide association ...
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    Genetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck. 

    Liu, Zhensheng; Wei, Qingyi; Zhou, Ziyuan; Sturgis, Erich M; Wang, Li-E; Li, Guojun (BMC cancer, 2012-05)
    The cooperation between phorbol 12-myristate 13-acetate induced protein 1 (NOXA) and myeloid cell leukemia 1 (MCL1) is critical in the intrinsic apoptotic pathway. Human papillomavirus 16 (HPV16), by inducing p53 and pRb-E2F ...
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    AuthorWei, Qingyi (70)Crump, John Andrew (19)Jin, Li (18)Krasuski, Richard Andrew (18)Peterson, Eric David (17)Fowler, Vance Garrison Jr (16)Liu, Zhensheng (16)Sturgis, Erich M (16)Ginsburg, Geoffrey Steven (14)Wang, Li-E (14)... View MoreDate Issued2010 - 2019 (426)2000 - 2009 (30)1984 - 1989 (1)TypeJournal article (456)Conference (1)SubjectHumans (457)
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