Now showing items 21-30 of 135
Patient detection of a drug dispensing error by use of physician-provided drug samples.
Serum C-Reactive Protein (CRP), Target for Therapy or Trouble?
(Biomark Insights, 2007-02-07)
High sensitivity serum C-reactive protein (hs-CRP) has come into clinical use as a marker of risk for cardiovascular disease (CVD). In addition to a role as a marker of disease, CRP has also been implicated in the pathogenesis ...
Comorbidity, age, race and stage at diagnosis in colorectal cancer: a retrospective, parallel analysis of two health systems.
(BMC Cancer, 2008-11-25)
BACKGROUND: Stage at diagnosis plays a significant role in colorectal cancer (CRC) survival. Understanding which factors contribute to a more advanced stage at diagnosis is vital to improving overall survival. Comorbidity, ...
Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate.
(Arthritis Res Ther, 2009)
INTRODUCTION: Aging proteins undergo non-enzymatic post-translational modification, including isomerization and racemization. We hypothesized that cartilage with many long-lived components could accumulate non-enzymatically ...
In vivo guidance and assessment of liver radio-frequency ablation with acoustic radiation force elastography.
(Ultrasound Med Biol, 2008-10)
The initial results from clinical trials investigating the utility of acoustic radiation force impulse (ARFI) imaging for use with radio-frequency ablation (RFA) procedures in the liver are presented. To date, data have ...
Prognostic biomarkers in individuals with prevalent coronary heart disease.
(Dis Markers, 2009)
Coronary disease is the leading killer of individuals worldwide and a leading cause of healthcare expenditure. On a global scale, ischemic heart disease kills over 6 million individuals each year and is projected by the ...
Meningococcemia in a patient coinfected with hepatitis C virus and HIV.
(Emerg Infect Dis, 2000-11)
We describe the first reported case of meningococcemia in a patient coinfected with hepatitis C virus and HIV. Hypocomplementemia secondary to hepatic dysfunction may have enhanced the patient's susceptibility to meningococcal ...
Early versus delayed fixed dose combination abacavir/lamivudine/zidovudine in patients with HIV and tuberculosis in Tanzania.
(AIDS Res Hum Retroviruses, 2009-12)
Fixed dose combination abacavir/lamivudine/zidovudine (ABC/3TC/ZDV) among HIV-1 and tuberculosis (TB)-coinfected patients was evaluated and outcomes between early vs. delayed initiation were compared. In a randomized, pilot ...
Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys.
(PLoS Pathog, 2009-12)
African green monkeys (AGM) and other natural hosts for simian immunodeficiency virus (SIV) do not develop an AIDS-like disease following SIV infection. To evaluate differences in the role of SIV-specific adaptive immune ...
Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2.
(PLoS One, 2008-02-06)
BACKGROUND: The lactogenic hormones prolactin (PRL) and placental lactogens (PL) play central roles in reproduction and mammary development. Their actions are mediated via binding to PRL receptor (PRLR), highly expressed ...