Now showing items 21-26 of 26
A cross-site, comparative effectiveness study of an integrated HIV and substance use treatment program.
(AIDS Patient Care STDS, 2010-10)
Co-occurrence of HIV and substance abuse is associated with poor outcomes for HIV-related health and substance use. Integration of substance use and medical care holds promise for HIV patients, yet few integrated treatment ...
Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality.
(Int J Chron Obstruct Pulmon Dis, 2014)
BACKGROUND: The respiratory tract is a major target of exposure to air pollutants, and respiratory diseases are associated with both short- and long-term exposures. We hypothesized that improved air quality in North Carolina ...
An integrated alcohol abuse and medical treatment model for patients with hepatitis C.
(Dig Dis Sci, 2012-04)
BACKGROUND: Patients with chronic hepatitis C virus (HCV) infection have high rates of alcohol consumption, which is associated with progression of fibrosis and lower response rates to HCV treatment. AIMS: This prospective ...
Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania.
(Am J Trop Med Hyg, 2012-01)
Consecutive febrile admissions were enrolled at two hospitals in Moshi, Tanzania. Confirmed acute Chikungunya virus (CHIKV), Dengue virus (DENV), and flavivirus infection were defined as a positive polymerase chain reaction ...
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.
(Circ Cardiovasc Genet, 2010-04)
BACKGROUND: Molecular tools may provide insight into cardiovascular risk. We assessed whether metabolites discriminate coronary artery disease (CAD) and predict risk of cardiovascular events. METHODS AND RESULTS: We performed ...
An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer.
(J Clin Invest, 2010-09)
Therapeutic anticancer vaccines are designed to boost patients' immune responses to tumors. One approach is to use a viral vector to deliver antigen to in situ DCs, which then activate tumor-specific T cell and antibody ...