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A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population.
(BMC cancer, 2011-01)
BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1
(APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1
promoter -141T/G variant (rs1760944) has been reported ...
On the interplay of telomeres, nevi and the risk of melanoma.
(PloS one, 2012-01)
The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres
have been found to be associated with many cancers and with number of nevi, a known
risk factor for melanoma. However, shorter telomeres ...
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
(PLoS genetics, 2011-03-17)
Genome-wide association studies (GWAS) have been successful in identifying common
genetic variation involved in susceptibility to etiologically complex disease. We
conducted a GWAS to identify common genetic variation involved ...
Illicit and nonmedical drug use among older adults: a review.
(Journal of aging and health, 2011-04)
Substance abuse among older adults is a looming public health concern. The number
of Americans aged 50+ years with a substance use disorder is projected to double from
2.8 million in 2002-2006 to 5.7 million in 2020. The ...
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.
(Subst Abuse Treat Prev Policy, 2012-03-20)
BACKGROUND: Although methadone has been used for the maintenance treatment of opioid
dependence for decades, it was not introduced in China or Taiwan until 2000s. Methadone-drug
interactions (MDIs) have been shown to cause ...
Predictors of latent tuberculosis treatment initiation and completion at a U.S. public health clinic: a prospective cohort study.
(BMC Public Health, 2012-06-21)
BACKGROUND: Treatment of latent tuberculosis infection (LTBI) is a key component in
U.S. tuberculosis control, assisted by recent improvements in LTBI diagnostics and
therapeutic regimens. Effectiveness of LTBI therapy, ...
Dietary Patterns Associated with Cognitive Function among the Older People in Underdeveloped Regions: Finding from the NCDFaC Study.
(Nutrients, 2018-04-09)
Although dietary patterns are crucial to cognitive function, associations of dietary
patterns with cognitive function have not yet been fully understood. This cross-sectional
study explored dietary patterns associated with ...
Trends in Drug Use-Associated Infective Endocarditis and Heart Valve Surgery, 2007 to 2017: A Study of Statewide Discharge Data.
(Annals of internal medicine, 2019-01)
Background:Drug use-associated infective endocarditis (DUA-IE) is increasing as a
result of the opioid epidemic. Infective endocarditis may require valve surgery, but
surgical treatment of DUA-IE has invoked controversy, ...
Fibroblast growth factor23 is associated with axonal integrity and neural network architecture in the human frontal lobes.
(PloS one, 2018-01)
Elevated levels of FGF23 in individuals with chronic kidney disease (CKD) are associated
with adverse health outcomes, such as increased mortality, large vessel disease, and
reduced white matter volume, cardiovascular and ...
Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population.
(Oncotarget, 2016-05)
The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated
cancers, including gastric cancer (GCa). We evaluated associations between 10 potentially
functional single nucleotide ...