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Now showing items 31-40 of 115
Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.
(J Hematol Oncol, 2018-03-04)
BACKGROUND: The binding of CXCR4 with its ligand (stromal-derived factor-1) maintains
hematopoietic stem/progenitor cells (HSPCs) in a quiescent state. We hypothesized
that blocking CXCR4/SDF-1 interaction after hematopoietic ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.
(Psychosom Med, 2010-04)
OBJECTIVES: To assess the effects of aerobic exercise training on neurocognitive performance.
Although the effects of exercise on neurocognition have been the subject of several
previous reviews and meta-analyses, they have ...
Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.
(PLoS One, 2017)
BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular
disease burden. The clinical profile and outcomes of AF patients with valvular heart
diseases in sub-Saharan Africa (SSA) have not ...
Age mediation of frontoparietal activation during visual feature search.
(Neuroimage, 2014-11-15)
Activation of frontal and parietal brain regions is associated with attentional control
during visual search. We used fMRI to characterize age-related differences in frontoparietal
activation in a highly efficient feature ...
Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.
(Arch Gen Psychiatry, 2012-11)
CONTEXT: Smaller hippocampal volumes are well established in posttraumatic stress
disorder (PTSD), but the relatively few studies of amygdala volume in PTSD have produced
equivocal results. OBJECTIVE: To assess a large cohort ...
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.
(Subst Abuse Treat Prev Policy, 2012-03-20)
BACKGROUND: Although methadone has been used for the maintenance treatment of opioid
dependence for decades, it was not introduced in China or Taiwan until 2000s. Methadone-drug
interactions (MDIs) have been shown to cause ...
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)
BACKGROUND: Disseminated tuberculosis is a major health problem in countries where
generalized human immunodeficiency virus (HIV) infection epidemics coincide with high
tuberculosis incidence rates; data are limited on patient ...
Changes in HIV risk behavior and seroincidence among clients presenting for repeat HIV counseling and testing in Moshi, Tanzania.
(AIDS Care, 2012)
While HIV counseling and testing (HCT) has been considered an HIV preventive measure
in Africa, data are limited describing behavior changes following HCT. This study
evaluated behavior changes and estimated HIV seroincidence ...
Brucellosis among hospitalized febrile patients in northern Tanzania.
(Am J Trop Med Hyg, 2012-12)
Acute and convalescent serum samples were collected from febrile inpatients identified
at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive
blood culture or a ≥ 4-fold increase in ...