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Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy.
(Int J Cancer, 2015-11-15)
Single nucleotide polymorphisms (SNPs) in the promoter region of FAS and FASLG may
alter their transcriptional activity. Thus, we determined the associations between
four FAS and FASLG promoter variants (FAS1377G>A, rs2234767; ...
A community-based intervention increases physical activity and reduces obesity in school-age children in North Carolina.
(Child Obes, 2015-06)
BACKGROUND: Community-based interventions are promising approaches to obesity prevention,
but few studies have prospectively evaluated them. The aim of this study was to evaluate
a natural experiment—a community intervention ...
Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence.
(Prostate Cancer Prostatic Dis, 2015-12)
BACKGROUND: Telomere-related genes play an important role in carcinogenesis and progression
of prostate cancer (PCa). It is not fully understood whether genetic variations in
telomere-related genes are associated with development ...
Pain Phenotypes and Associated Clinical Risk Factors Following Traumatic Amputation: Results from Veterans Integrated Pain Evaluation Research (VIPER).
(Pain medicine (Malden, Mass.), 2016-01)
OBJECTIVE:To define clinical phenotypes of postamputation pain and identify markers
of risk for the development of chronic pain. DESIGN:Cross-sectional study of military
service members enrolled 3-18 months after traumatic ...
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
(Pain Med, 2016-01)
BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans,
many of whom continue to experience persistent pain symptoms despite multiple pharmacological
interventions. Preclinical data suggest ...
Worksite medical home: health services use and claim costs.
(Am J Manag Care, 2015-07-01)
OBJECTIVES: To examine the relationship among use of an on-site employer-provided
primary care medical home, and health services use and health plan costs for inpatient
and outpatient services and pharmaceuticals. STUDY ...
Improving Outcomes in Colorectal Surgery by Sequential Implementation of Multiple Standardized Care Programs.
(J Am Coll Surg, 2015-08)
BACKGROUND: The purpose of this study was to examine the impact of the sequential
implementation of the enhanced recovery program (ERP) and surgical site infection
bundle (SSIB) on short-term outcomes in colorectal surgery ...
Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal.
(PLoS Pathog, 2014-08)
Ongoing Cryptococcus gattii outbreaks in the Western United States and Canada illustrate
the impact of environmental reservoirs and both clonal and recombining propagation
in driving emergence and expansion of microbial ...
Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.
(PLoS One, 2014)
Subtle behavioral and cognitive deficits have been documented in patient cohorts with
orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated
with structural brain abnormalities but have ...
The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer.
(PloS one, 2013-01)
TNFAIP2 is a crucial gene involved in apoptosis. Single nucleotide polymorphisms (SNPs)
in its miRNA binding sites could modulate functions of the miRNA-target genes and
thus risk of cancers. In this study, we investigated ...