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Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
(Pain Med, 2016-01)
BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans,
many of whom continue to experience persistent pain symptoms despite multiple pharmacological
interventions. Preclinical data suggest ...
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans.
(Genome Biol, 2015-09-17)
BACKGROUND: Cellular senescence is a stable arrest of proliferation and is considered
a key component of processes associated with carcinogenesis and other ageing-related
phenotypes. Here, we perform methylome analysis of ...
Worksite medical home: health services use and claim costs.
(Am J Manag Care, 2015-07-01)
OBJECTIVES: To examine the relationship among use of an on-site employer-provided
primary care medical home, and health services use and health plan costs for inpatient
and outpatient services and pharmaceuticals. STUDY ...
Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.
(J Virol, 2015-10)
UNLABELLED: Infants born to HIV-1-infected mothers in resource-limited areas where
replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout
breastfeeding. Despite this, the majority of infants ...
Improving Outcomes in Colorectal Surgery by Sequential Implementation of Multiple Standardized Care Programs.
(J Am Coll Surg, 2015-08)
BACKGROUND: The purpose of this study was to examine the impact of the sequential
implementation of the enhanced recovery program (ERP) and surgical site infection
bundle (SSIB) on short-term outcomes in colorectal surgery ...
Patterns of care quality and prognosis among hospitalized ischemic stroke patients with chronic kidney disease.
(J Am Heart Assoc, 2014-06-05)
BACKGROUND: Relatively little is known about the quality of care and outcomes for
hospitalized ischemic stroke patients with chronic kidney disease (CKD). We examined
quality of care and in-hospital prognoses among patients ...
A randomized Phase 2 trial of telavancin versus standard therapy in patients with uncomplicated Staphylococcus aureus bacteremia: the ASSURE study.
(BMC Infect Dis, 2014-05-23)
BACKGROUND: Staphylococcus aureus bacteremia is a common infection associated with
significant morbidity and mortality. Telavancin is a bactericidal lipoglycopeptide
active against Gram-positive pathogens, including ...
Is chronic asthma associated with shorter leukocyte telomere length at midlife?
(Am J Respir Crit Care Med, 2014-08-15)
RATIONALE: Asthma is prospectively associated with age-related chronic diseases and
mortality, suggesting the hypothesis that asthma may relate to a general, multisystem
phenotype of accelerated aging. OBJECTIVES: To test ...
Contemporary trends and predictors of postacute service use and routine discharge home after stroke.
(J Am Heart Assoc, 2015-02-23)
BACKGROUND: Returning home after the hospital is a primary aim for healthcare; however,
additional postacute care (PAC) services are sometimes necessary for returning stroke
patients to their pre-event status. Recent trends ...
Nonmedical Opioid Pain Relievers and All-Cause Mortality: A 27-Year Follow-Up From the Epidemiologic Catchment Area Study.
(American journal of public health, 2016-03)
We investigated whether nonmedical opioid pain reliever use is associated with higher
mortality in the general US population.We assessed the history of nonmedical opioid
pain reliever use among 9985 people interviewed at ...