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Bevacizumab continuation beyond initial bevacizumab progression among recurrent glioblastoma patients.
(Br J Cancer, 2012-10-23)
BACKGROUND: Bevacizumab improves outcome for most recurrent glioblastoma patients,
but the duration of benefit is limited and survival after initial bevacizumab progression
is poor. We evaluated bevacizumab continuation ...
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)
BACKGROUND: Disseminated tuberculosis is a major health problem in countries where
generalized human immunodeficiency virus (HIV) infection epidemics coincide with high
tuberculosis incidence rates; data are limited on patient ...
Variability in frontotemporal brain structure: the importance of recruitment of African Americans in neuroscience research.
(PLoS One, 2010-10-26)
BACKGROUND: Variation in brain structure is both genetically and environmentally influenced.
The question about potential differences in brain anatomy across populations of differing
race and ethnicity remains a controversial ...
Does surgery improve outcomes for esophageal squamous cell carcinoma? An analysis using the surveillance epidemiology and end results registry from 1998 to 2008.
(J Am Coll Surg, 2012-11)
BACKGROUND: We examined survival associated with locally advanced esophageal squamous
cell cancer (SCC) to evaluate if treatment without surgery could be considered adequate.
STUDY DESIGN: Patients in the Surveillance, ...
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.
(PLoS One, 2008-01-02)
PURPOSE: To define the biology driving the aggressive nature of breast cancer arising
in young women. EXPERIMENTAL DESIGN: Among 784 patients with early stage breast cancer,
using prospectively-defined, age-specific cohorts ...
Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings.
(AIDS, 2012-07-17)
OBJECTIVE: To evaluate virologic response rates of lopinavir/ritonavir (LPV/r) monotherapy
as second-line antiretroviral treatment (ART) among adults in resource-limited settings
(RLSs). DESIGN: An open-label pilot study ...
Leptospirosis among hospitalized febrile patients in northern Tanzania.
(Am J Trop Med Hyg, 2011-08)
We enrolled consecutive febrile admissions to two hospitals in Moshi, Tanzania. Confirmed
leptospirosis was defined as a ≥ 4-fold increase in microscopic agglutination test
(MAT) titer; probable leptospirosis as reciprocal ...
The design of an observational study of hypertension management, adherence and pressure control in Blood Pressure Success Zone Program participants.
(Int J Clin Pract, 2008-09)
AIMS: The Blood Pressure Success Zone (BPSZ) Program, a nationwide initiative, provides
education in addition to a complimentary trial of one of three antihypertensive medications.
The BPSZ Longitudinal Observational Study ...
Action video game playing is associated with improved visual sensitivity, but not alterations in visual sensory memory.
(Atten Percept Psychophys, 2013-08)
Action video game playing has been experimentally linked to a number of perceptual
and cognitive improvements. These benefits are captured through a wide range of psychometric
tasks and have led to the proposition that action ...
Leptospirosis and human immunodeficiency virus co-infection among febrile inpatients in northern Tanzania.
(Vector Borne Zoonotic Dis, 2013-08)
BACKGROUND: Leptospirosis and human immunodeficiency virus (HIV) infection are prevalent
in many areas, including northern Tanzania, yet little is known about their interaction.
METHODS: We enrolled febrile inpatients at ...