Now showing items 41-50 of 963
An Initial Evaluation of the Impact of Pokémon GO on Physical Activity.
(Journal of the American Heart Association, 2017-05-16)
Pokémon GO is a location-based augmented reality game. Using GPS and the camera on a smartphone, the game requires players to travel in real world to capture animated creatures, called Pokémon. We examined the impact of ...
Confounders versus Mediators: An Important Distinction.
The Digital Drag and Drop Pillbox: Design and Feasibility of a Skill-based Education Model to Improve Medication Management.
(The Journal of cardiovascular nursing, 2017-09)
We present the design and feasibility testing for the "Digital Drag and Drop Pillbox" (D-3 Pillbox), a skill-based educational approach that engages patients and providers, measures performance, and generates reports of ...
Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization.
Despite recent advances, many cancers remain refractory to available immunotherapeutic strategies. Emerging evidence indicates that the tolerization of local dendritic cells (DCs) within the tumor microenvironment promotes ...
A Transcriptional Signature Identifies LKB1 Functional Status as a Novel Determinant of MEK Sensitivity in Lung Adenocarcinoma.
(Cancer research, 2017-01)
LKB1 is a commonly mutated tumor suppressor in non-small cell lung cancer that exerts complex effects on signal transduction and transcriptional regulation. To better understand the downstream impact of loss of functional ...
The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells).
(International urology and nephrology, 2015-12)
The urothelium is a frontline sensor of the lower urinary tract, sampling the bladder lumen and stimulating an immune response to infectious and noxious agents. Pattern recognition receptors (PRRs) recognize such agents ...
Exposure to opposing views on social media can increase political polarization.
(Proceedings of the National Academy of Sciences of the United States of America, 2018-09)
There is mounting concern that social media sites contribute to political polarization by creating "echo chambers" that insulate people from opposing views about current events. We surveyed a large sample of Democrats and ...
A pilot investigation of audiovisual processing and multisensory integration in patients with inherited retinal dystrophies.
(BMC ophthalmology, 2017-12-07)
In this study, we examined audiovisual (AV) processing in normal and visually impaired individuals who exhibit partial loss of vision due to inherited retinal dystrophies (IRDs).Two groups were analyzed for this pilot study: ...
TNFRSF1B +676 T>G polymorphism predicts survival of non-small cell lung cancer patients treated with chemoradiotherapy.
(BMC cancer, 2011-10-14)
The dysregulation of gene expression in the TNF-TNFR superfamily has been involved in various human cancers including non-small cell lung cancer (NSCLC). Furthermore, functional polymorphisms in TNF-α and TNFRSF1B genes ...
Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden.
(PloS one, 2017-01)
Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide ...