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Pre-miRNA variants as predictors of clinical outcome in patients with squamous cell carcinomas of the nonoropharynx.
(Oncotarget, 2016-05)
Functional polymorphisms of miRNAs may affect the function and target expression of
miRNAs, which can, in turn, affect the biological activity, etiology, and prognosis
of cancer. We hypothesized that four common polymorphisms ...
Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population.
(Oncotarget, 2016-12)
Interleukin-17 plays a crucial role in inflammation-related carcinogenesis. We hypothesize
that genetic variants in IL-17 are associated with gastric cancer (GCa) risk, and
we genotyped five potentially functional single ...
Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population.
(PloS one, 2012-01)
BACKGROUND: Recent genome-wide association studies (GWAS) have found a single nucleotide
polymorphism (SNP, rs2274223 A>G) in PLCE1 to be associated with risk of gastric adenocarcinoma.
In the present study, we validated ...
Tumor necrosis factor-α induced protein 8 polymorphism and risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study.
(PloS one, 2012-01)
BACKGROUND: Non-Hodgkin's lymphoma (NHL) has been reported to be associated with autoimmune
and pro-inflammatory response, and genetic polymorphisms of candidate genes involved
in autoimmune and pro-inflammatory response ...
Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer.
(Oncotarget, 2016-05)
The JNK and P38α pathways play a crucial role in tissue homeostasis, apoptosis and
autophagy under genotoxic stresses, but it is unclear whether single nucleotide polymorphisms
(SNPs) of genes in these pathways play a role ...