Now showing items 8391-8400 of 8478
Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density.
(Nature communications, 2018-03-02)
B cells expressing high affinity antigen receptors are advantaged in germinal centers (GC), perhaps by increased acquisition of antigen for presentation to follicular helper T cells and improved T-cell help. In this model ...
The expanded role of fatty acid metabolism in cancer: new aspects and targets
(Precision Clinical Medicine, 2019-10-01)
<jats:title>Abstract</jats:title> <jats:p>Cancer cells undergo metabolic reprogramming to support cell proliferation, growth, and dissemination. Alterations in lipid metabolism, and specifically the uptake ...
Hip extensor mechanics and the evolution of walking and climbing capabilities in humans, apes, and fossil hominins.
(Proceedings of the National Academy of Sciences of the United States of America, 2018-04-02)
The evolutionary emergence of humans' remarkably economical walking gait remains a focus of research and debate, but experimentally validated approaches linking locomotor capability to postcranial anatomy are limited. In ...
Beyoncé’s Soft Power
(Camera Obscura: Feminism, Culture, and Media Studies, 2019-09-01)
<jats:p>This article charts Beyoncé’s multimedia intervention into the politics of the Trump presidency as she draws on the work of black Muslim and Latinx artists to challenge white monopolies on representation in the Breitbart ...
Collective PES: More than the sum of individual incentives
(Environmental Science & Policy, 2019-12)
Incidence, Characteristics, and Outcomes of Myocardial Infarction in Patients With Peripheral Artery Disease: Insights From the EUCLID Trial.
(JAMA cardiology, 2019-01)
Importance:Patients with peripheral artery disease (PAD) are at high risk for myocardial infarction (MI). Objective:To characterize the incidence and types of MI in a PAD population, identify factors associated with MI, ...
Cardiovascular Outcomes After Lower Extremity Endovascular or Surgical Revascularization: The EUCLID Trial.
(Journal of the American College of Cardiology, 2018-10)
BACKGROUND:Lower extremity revascularization (LER) is a common treatment in patients with peripheral artery disease (PAD), but long-term outcomes are poorly defined. OBJECTIVES:The aim was to analyze LER in the EUCLID (Examining ...
Outcomes of Patients with Critical Limb Ischaemia in the EUCLID Trial.
(European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2018-01)
OBJECTIVES:Critical limb ischaemia (CLI) implies an increased risk of cardiovascular morbidity and mortality, and the optimal antithrombotic treatment is not established. DESIGN, MATERIALS, METHODS:The EUCLID trial investigated ...
Ticagrelor versus clopidogrel in patients with symptomatic peripheral artery disease and prior coronary artery disease: Insights from the EUCLID trial.
(Vascular medicine (London, England), 2018-12)
Patients with peripheral artery disease (PAD) are at heightened risk of cardiovascular morbidity and mortality. We sought to evaluate the risk of concomitant coronary artery disease (CAD) in patients with symptomatic PAD ...
Finding Means to Fulfill the Societal and Academic Imperative for Open Data Access and Sharing.
(JAMA cardiology, 2018-09)