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Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.
(J Am Heart Assoc, 2013-11-25)
BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis
in atrial fibrillation. Adoption patterns of this new agent in community practice
are unknown. METHODS AND RESULTS: We studied patterns ...
A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke.
(J Am Heart Assoc, 2013-01-28)
BACKGROUND: We aimed to derive and validate a single risk score for predicting death
from ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage
(SAH). METHODS AND RESULTS: Data from 333 865 stroke ...
Comparison of performance achievement award recognition with primary stroke center certification for acute ischemic stroke care.
(J Am Heart Assoc, 2013-10-14)
BACKGROUND: Hospital certification and recognition programs represent 2 independent
but commonly used systems to distinguish hospitals, yet they have not been directly
compared. This study assessed acute ischemic stroke ...
Alglucosidase alfa enzyme replacement therapy as a therapeutic approach for glycogen storage disease type III.
(Mol Genet Metab, 2013-02)
We investigated the feasibility of using recombinant human acid-α glucosidase (rhGAA,
Alglucosidase alfa), an FDA approved therapy for Pompe disease, as a treatment approach
for glycogen storage disease type III (GSD III). ...
A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.
(PLoS One, 2013)
There is great potential for host-based gene expression analysis to impact the early
diagnosis of infectious diseases. In particular, the influenza pandemic of 2009 highlighted
the challenges and limitations of traditional ...
Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.
(J Am Heart Assoc, 2013-03-19)
BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD)
patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence
of depression and anxiety. We examined whether ...
PINOT NOIR: pulmonic insufficiency improvement with nitric oxide inhalational response.
(J Cardiovasc Magn Reson, 2013-09-04)
BACKGROUND: Tetralogy of Fallot (TOF) repair and pulmonary valvotomy for pulmonary
stenosis (PS) lead to progressive pulmonary insufficiency (PI), right ventricular
enlargement and dysfunction. This study assessed whether ...
Embolization of patent foramen ovale closure devices: incidence, role of imaging in identification, potential causes, and management.
(Tex Heart Inst J, 2013)
Transcatheter patent foramen ovale (PFO) closure is an alternative to antiplatelet
or anticoagulative therapy in patients with cryptogenic stroke, and it is associated
with a small incidence of periprocedural sequelae. Because ...
Migraine headaches following mitral valvuloplasty: Koch's postulates finally satisfied?
(J Invasive Cardiol, 2013-06)
The relationship between patent foramen ovale and migraine headache is a topic surrounded
by much controversy. We present the case of a 45-year-old woman who underwent successful
percutaneous mitral balloon valvuloplasty ...
