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Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.
(PLoS One, 2013)
BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition
with estimated 30% mortality. Clinical outcomes for patients with severe infections
improve when antibiotics are appropriately chosen ...
Effect of socioeconomic status as measured by education level on survival in breast cancer clinical trials.
(Psychooncology, 2013-02)
OBJECTIVES: This paper aims to investigate the effect of socioeconomic status, as
measured by education, on the survival of breast cancer patients treated on 10 studies
conducted by the Cancer and Leukemia Group B. METHODS: ...
The role of lipid-related genes, aging-related processes, and environment in healthspan.
(Aging Cell, 2013-04)
The inherent complexity of aging-related traits can temper progress in unraveling
the genetic origins of healthspan. We focus on two generations in the Framingham Heart
Study, the original (FHS) and offspring (FHSO) cohorts, ...
Estimating leptospirosis incidence using hospital-based surveillance and a population-based health care utilization survey in Tanzania.
(PLoS Negl Trop Dis, 2013)
BACKGROUND: The incidence of leptospirosis, a neglected zoonotic disease, is uncertain
in Tanzania and much of sub-Saharan Africa, resulting in scarce data on which to prioritize
resources for public health interventions ...
Perceived stress and biological risk: is the link stronger in Russians than in Taiwanese and Americans?
(Stress, 2013-07)
Allostatic load theory implies a relationship between exposure to psychological stress
and multi-system physiological dysregulation. We used data from population-based samples
of men and women in Russia (Moscow; n = 1800; ...
Leptospirosis and human immunodeficiency virus co-infection among febrile inpatients in northern Tanzania.
(Vector Borne Zoonotic Dis, 2013-08)
BACKGROUND: Leptospirosis and human immunodeficiency virus (HIV) infection are prevalent
in many areas, including northern Tanzania, yet little is known about their interaction.
METHODS: We enrolled febrile inpatients at ...
Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone.
(Bone Marrow Transplant, 2013-11)
Chemotherapy plus G-CSF (C+G) and G-CSF alone are two of the most common methods used
to mobilize CD34(+) cells for autologous hematopoietic SCT (AHSCT). In order to compare
and determine the real-world outcomes and costs ...
Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.
(PLoS One, 2013)
Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and
uncertainty lead to treatment delays and inappropriate antibiotic use. A growing literature
suggests the host's inflammatory response to the ...
Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans.
(Hum Brain Mapp, 2013-11)
Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in
Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic
mild TBI in military veterans relies on obtaining an ...
Comparing actual and perceived causes of fever among community members in a low malaria transmission setting in northern Tanzania.
(Trop Med Int Health, 2013-11)
OBJECTIVE: To compare actual and perceived causes of fever in northern Tanzania. METHODS:
In a standardised survey, heads of households in 30 wards in Moshi, Tanzania, were
asked to identify the most common cause of fever ...