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    Genome-wide expression profiles of subchondral bone in osteoarthritis. 

    Chang, JH; Chen, YT; Chou, CH; Chuang, HP; Kraus, Virginia Byers; Kuo, SY; Lee, CH; ... (12 authors) (Arthritis Res Ther, 2013)
    INTRODUCTION: The aim of this study was to evaluate, for the first time, the differences in gene expression profiles of normal and osteoarthritic (OA) subchondral bone in human subjects. METHODS: Following histological assessment ...
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    Relationships amongst osteoarthritis biomarkers, dynamic knee joint load, and exercise: results from a randomized controlled pilot study. 

    Cibere, J; Huebner, JL; Hunt, MA; Kraus, Virginia Byers; Peters, S; Pollock, CL; Saxne, T; ... (8 authors) (BMC Musculoskelet Disord, 2013-03-27)
    BACKGROUND: Little is known about the relationships of circulating levels of biomarkers of cartilage degradation with biomechanical outcomes relevant to knee osteoarthritis (OA) or biomarker changes following non-pharmacological ...
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    Estimating leptospirosis incidence using hospital-based surveillance and a population-based health care utilization survey in Tanzania. 

    Biggs, HM; Crump, John Andrew; Galloway, RL; Hertz, JT; Marks, Florian; Maro, Venance P; Munishi, Oresto Michael; ... (8 authors) (PLoS Negl Trop Dis, 2013)
    BACKGROUND: The incidence of leptospirosis, a neglected zoonotic disease, is uncertain in Tanzania and much of sub-Saharan Africa, resulting in scarce data on which to prioritize resources for public health interventions ...
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    Leptospirosis and human immunodeficiency virus co-infection among febrile inpatients in northern Tanzania. 

    Biggs, HM; Bui, DM; Crump, John Andrew; Galloway, RL; Maro, Venance P; Morrissey, AB (Vector Borne Zoonotic Dis, 2013-08)
    BACKGROUND: Leptospirosis and human immunodeficiency virus (HIV) infection are prevalent in many areas, including northern Tanzania, yet little is known about their interaction. METHODS: We enrolled febrile inpatients at ...
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    Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone. 

    Bernard, LM; Brown, S; Carrum, G; Chao, Nelson J; Grima, DT; Holmberg, L; Horwitz, Mitchell; ... (13 authors) (Bone Marrow Transplant, 2013-11)
    Chemotherapy plus G-CSF (C+G) and G-CSF alone are two of the most common methods used to mobilize CD34(+) cells for autologous hematopoietic SCT (AHSCT). In order to compare and determine the real-world outcomes and costs ...
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    Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans. 

    Ahn, SH; Cairns, CB; Cyr, Derek; Fowler, Vance Garrison Jr; Ginsburg, Geoffrey Steven; Glickman, Seth W; Kingsmore, Stephen F; ... (17 authors) (PLoS One, 2013)
    Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and uncertainty lead to treatment delays and inappropriate antibiotic use. A growing literature suggests the host's inflammatory response to the ...
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    Comparing actual and perceived causes of fever among community members in a low malaria transmission setting in northern Tanzania. 

    Crump, John Andrew; Hertz, JT; Munishi, Oresto Michael; Reddy, Elizabeth A; Sharp, JP (Trop Med Int Health, 2013-11)
    OBJECTIVE: To compare actual and perceived causes of fever in northern Tanzania. METHODS: In a standardised survey, heads of households in 30 wards in Moshi, Tanzania, were asked to identify the most common cause of fever ...
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    Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma. 

    Bailey, L; Coan, A; Desjardins, A; Friedman, HS; Herndon, James Emmett II; Lipp, Eric S; Lou, E; ... (12 authors) (Cancer Med, 2013-04)
    Patients with unresectable glioblastomas have a poor prognosis, with median survival of 6-10 months. We conducted a phase II trial of upfront 5-day temozolomide (TMZ) and bevacizumab (BV) in patients with newly diagnosed ...
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    Biomarkers to help guide management of patients with pulmonary nodules. 

    Campa, Michael Joseph; Eisenberg, M; Gottlin, EB; Grant, RP; Herndon, James Emmett II; Kafader, D; Patz, EF; ... (8 authors) (Am J Respir Crit Care Med, 2013-08-15)
    RATIONALE: Indeterminate pulmonary nodules are a common radiographic finding and require further evaluation because of the concern for lung cancer. OBJECTIVES: We developed an algorithm to assign patients to a low- or high-risk ...
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    Chikungunya as a cause of acute febrile illness in southern Sri Lanka. 

    Akoroda, U; Bodinayake, Champica K; Chow, A; Chua, R; Devasiri, V; Gubler, DJ; Hou, Y; ... (14 authors) (PLoS One, 2013)
    BACKGROUND: Chikungunya virus (CHIKV) re-emerged in Sri Lanka in late 2006 after a 40-year hiatus. We sought to identify and characterize acute chikungunya infection (CHIK) in patients presenting with acute undifferentiated ...
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    AuthorCrump, John Andrew (4)Galloway, RL (3)Maro, Venance P (3)Ai, Weiyun (2)Bhagat, Govind (2)Biggs, HM (2)Chiu, April (2)Choi, William WL (2)Dybkaer, Karen (2)Ferreri, Andrés JM (2)... View MoreDate Issued
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